{"id":"W2148760132","doi":"10.1093/nar/gkf398","title":"The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides","year":2002,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":315,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Zinc finger; Biology; DNA methylation; DNA; Consensus sequence; Binding site; Promoter; Cell biology; Transcription factor; Gene; Biochemistry; Peptide sequence; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006370211,0.0003594984,0.0001782723,0.0002386725,0.0002159945,0.0002507728,0.0002209059,0.000328397,0.001765711],"category_scores_gemma":[0.0001527345,0.0001191172,0.0001945043,0.0001374382,0.0001725773,0.0001878814,0.000295125,0.0004308802,0.0006494382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002590281,"about_ca_system_score_gemma":0.0001167026,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003603036,"about_ca_topic_score_gemma":0.0004760083,"domain_scores_codex":[0.9998842,0.00001201636,0.000004895513,0.0000356821,0.00003828704,0.00002488319],"domain_scores_gemma":[0.9999229,0.00001191938,0.00002512105,0.000005641683,0.000008040679,0.00002642163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002590217,0.000005996083,0.0001992525,0.00001410773,0.000001878892,0.00002666282,0.000004919629,0.00001918697,0.9989329,0.00004614727,0.00002085876,0.0007020414],"study_design_scores_gemma":[0.00001676592,0.0002179544,0.01630835,0.00001052663,0.00001382602,0.001894916,0.00003842803,0.001336316,0.9724172,0.0001558128,0.007577035,0.00001285121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880881,0.00216257,0.007501422,0.00007304111,0.00001502031,0.00003312557,0.0003233324,0.0001022805,0.001701133],"genre_scores_gemma":[0.9941912,0.0004760523,0.002600841,0.00003312193,0.000009544038,0.00002069677,0.0008642696,0.000009707859,0.001794517],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001765711,"threshold_uncertainty_score":0.00590682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08674780694806115,"score_gpt":0.320604747547083,"score_spread":0.2338569405990218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}