{"id":"W2148795098","doi":"10.1161/hy0202.103481","title":"Fibrosis, Matrix Metalloproteinases, and Inflammation in the Heart of DOCA-Salt Hypertensive Rats: Role of ET <sub>A</sub> Receptors","year":2002,"lang":"en","type":"article","venue":"Hypertension","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"Shriners Hospitals for Children - Canada; Canadian Institutes of Health Research; Montreal Clinical Research Institute","funders":"Hypertension Canada","keywords":"Fibronectin; Matrix metalloproteinase; Endocrinology; Extracellular matrix; Internal medicine; Cardiac fibrosis; Fibrosis; Cell adhesion molecule; Inflammation; Proinflammatory cytokine; Endothelin 1; Endothelin receptor; Receptor; Medicine; Receptor antagonist; Chemistry; Antagonist; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000203219,0.0006590042,0.000701129,0.0006244212,0.0002835453,0.0003217621,0.0001428376,0.0004185626,0.001340406],"category_scores_gemma":[0.000112299,0.0003798027,0.0003777731,0.0002196998,0.0004227375,0.0003624109,0.0001791899,0.0009664932,0.0002617682],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003115245,"about_ca_system_score_gemma":0.0002663745,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593901,"about_ca_topic_score_gemma":0.003215967,"domain_scores_codex":[0.9998335,0.00002160181,0.00001499196,0.0000306418,0.00003586615,0.00006335496],"domain_scores_gemma":[0.9996862,0.00001991913,0.0000580732,0.00002177947,0.00002032196,0.0001936148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003413628,0.0002491338,0.001760013,0.00004215591,0.0000199494,0.0001275862,0.00003258022,0.00002103419,0.9926488,0.00003703552,0.00004404494,0.001603941],"study_design_scores_gemma":[0.0006990598,0.006677404,0.2722848,0.0000264162,0.0002908232,0.0008796265,0.000382157,0.001314452,0.7153807,0.0001531991,0.001862254,0.00004904212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972525,0.001537132,0.0003488198,0.00012009,0.00004006182,0.00001289489,0.0001896999,0.00002516519,0.0004736207],"genre_scores_gemma":[0.9917271,0.002655398,0.001285644,0.0001559366,0.00008326589,0.00010551,0.0004454732,0.00001379402,0.003527945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593901,"threshold_uncertainty_score":0.004484177,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009999623053575263,"score_gpt":0.2088019278949448,"score_spread":0.1988023048413695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}