{"id":"W2148800631","doi":"10.1021/jo030347v","title":"Synthesis of (±)-Hamigeran B, (−)-Hamigeran B, and (±)-1<i>-epi</i>-Hamigeran B:  Use of Bulky Silyl Groups to Protect a Benzylic Carbon−Oxygen Bond from Hydrogenolysis","year":2004,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Hydrogenolysis; Enone; Chemistry; Natural product; Silylation; Selectivity; Oxygen; Carbon fibers; Organic chemistry; Stereochemistry; Catalysis; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005424377,0.0003352251,0.0006307246,0.00006653838,0.0000794068,0.00002458706,0.0005415245,0.0002296505,0.00006318072],"category_scores_gemma":[0.0005525533,0.0002504083,0.0002235265,0.0003240106,0.000163192,0.00001581306,0.0002752905,0.0003473498,8.631352e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005115187,"about_ca_system_score_gemma":0.0002031369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004345386,"about_ca_topic_score_gemma":0.00007755101,"domain_scores_codex":[0.9981024,0.00004661753,0.0008013771,0.0003411569,0.0003922445,0.0003162305],"domain_scores_gemma":[0.9979858,0.0001024642,0.0006918277,0.0007258496,0.0002911826,0.0002028159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007647366,0.0001227211,0.0004668457,0.0001185466,0.0004008146,0.00000583761,0.0002831929,0.0001550691,0.9967878,0.000001024284,0.00008784372,0.0008055231],"study_design_scores_gemma":[0.0008408398,0.0003598513,0.00160189,0.0001308057,0.0002777232,0.0001137095,0.000155796,0.00000799819,0.9957206,0.0001148007,0.0004097644,0.0002662838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965852,0.002091091,0.00004900358,0.0008397879,0.00005831924,0.0002527102,0.00005265487,0.000007256375,0.00006390759],"genre_scores_gemma":[0.9979823,0.0007983533,0.0005959819,0.00008633112,0.0003684582,0.000004025389,0.00001397374,0.00005298879,0.0000975607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001397057,"threshold_uncertainty_score":0.9999948,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006564814910978939,"score_gpt":0.1956052940702998,"score_spread":0.1890404791593209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}