{"id":"W2148810272","doi":"10.1002/pmic.200400970","title":"Increased quantitative proteome coverage with <sup>13</sup>C/<sup>12</sup>C‐based, acid‐cleavable isotope‐coded affinity tag reagent and modified data acquisition scheme","year":2005,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":112,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute","keywords":"Chemistry; Reagent; Chromatography; Proteome; Mass spectrometry; Tandem mass spectrometry; Electrospray ionization; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006456265,0.0006847849,0.0006507241,0.0001417237,0.0005886048,0.0002550849,0.00102847,0.0003600377,0.0003460587],"category_scores_gemma":[0.0002080372,0.000664884,0.00009836411,0.0003386,0.0003143334,0.00102418,0.0006153215,0.0008622252,0.00005552572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003183101,"about_ca_system_score_gemma":0.0002981397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003234065,"about_ca_topic_score_gemma":0.00003752836,"domain_scores_codex":[0.9964159,0.00009411675,0.0007713262,0.001442357,0.0005034655,0.0007728452],"domain_scores_gemma":[0.996478,0.0001496608,0.0005327288,0.002224399,0.0002589134,0.000356297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005818025,0.002295341,0.004310771,0.0013914,0.0004515145,0.00005587282,0.001347216,0.07503356,0.8902269,0.01327745,0.001543421,0.004248535],"study_design_scores_gemma":[0.003027168,0.0001908294,0.00005488942,0.0002407797,0.00009090149,0.00002979595,0.0001530709,0.4450164,0.5439985,0.004081144,0.002191132,0.0009253257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6991311,0.0001410047,0.2914804,0.0008370121,0.000005399578,0.003379797,0.001540718,0.0005812944,0.002903348],"genre_scores_gemma":[0.5363576,0.000132054,0.4597117,0.0003334779,0.0001426071,0.001760229,0.001244396,0.0001085775,0.0002093632],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3699828,"threshold_uncertainty_score":0.9995803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03443276875391796,"score_gpt":0.2830345931396627,"score_spread":0.2486018243857447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}