{"id":"W2148810822","doi":"10.1177/0192623311406935","title":"An Analysis of Pharmaceutical Experience with Decades of Rat Carcinogenicity Testing","year":2011,"lang":"en","type":"article","venue":"Toxicologic Pathology","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"ca_institutions":"L'Alliance Boviteq","funders":"","keywords":"Carcinogen; Medicine; International agency; Toxicology; Pharmacology; Pathology; Cancer; Internal medicine; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01675507,0.0003526931,0.0004465852,0.001811777,0.0004538043,0.0006665342,0.0006364196,0.000605871,0.001229799],"category_scores_gemma":[0.04778158,0.0002136031,0.0006784045,0.0009609213,0.0007739231,0.0008212028,0.0011905,0.0004776341,0.000579208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007720318,"about_ca_system_score_gemma":0.0006781924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005720006,"about_ca_topic_score_gemma":0.001172137,"domain_scores_codex":[0.9865571,0.005456779,0.001467105,0.00110896,0.004873282,0.0005367524],"domain_scores_gemma":[0.9198853,0.04360421,0.02059317,0.005512126,0.008522644,0.001882545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009679957,0.0003241223,0.9093263,0.0001337722,0.0001485727,0.0005574502,0.0008431346,0.0006475974,0.006150063,0.0001709285,0.0003356666,0.08039439],"study_design_scores_gemma":[0.00004669256,0.01304056,0.9553304,0.0000957501,0.0002405569,0.005768151,0.001030191,0.002181301,0.01337553,0.0003804786,0.008437492,0.00007296061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935926,0.001729122,0.002112459,0.0001710198,0.00002310205,0.00005147085,0.0001358025,0.00003468079,0.002149736],"genre_scores_gemma":[0.9953268,0.001216768,0.001891407,0.0002054869,0.00004828523,0.00004117309,0.0003788775,0.00001187959,0.0008792933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01675507,"threshold_uncertainty_score":0.08861035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.078396039961139,"score_gpt":0.3381189894626682,"score_spread":0.2597229495015292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}