{"id":"W2148847026","doi":"10.1128/aac.49.11.4608-4615.2005","title":"Mechanisms of Azole Resistance in a Clinical Isolate of <i>Candida tropicalis</i>","year":2005,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":141,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ministère des Transports","funders":"","keywords":"Biology; Efflux; Candida tropicalis; Rhodamine 123; Microbiology; Azole; Major facilitator superfamily; Gene; Yeast; Molecular biology; Drug resistance; Candida albicans; Mutant; Genetics; Multiple drug resistance; Antifungal","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001495762,0.000376755,0.0003541361,0.0003113642,0.0001776648,0.00039969,0.0002076242,0.0003495682,0.000520958],"category_scores_gemma":[0.0003667437,0.00007497974,0.0002782516,0.0002300448,0.0002093097,0.0001349296,0.0001543821,0.0002999739,0.0001937966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002475194,"about_ca_system_score_gemma":0.0001702429,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001465247,"about_ca_topic_score_gemma":0.0008222978,"domain_scores_codex":[0.9997944,0.00002692963,0.00003052255,0.00005994096,0.00004951993,0.00003874858],"domain_scores_gemma":[0.9997657,0.00006438261,0.00008026404,0.00001737257,0.00004340052,0.00002891366],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001737546,0.00003146767,0.009934447,0.000159296,0.0000166745,0.001811978,0.00007072574,0.00007080011,0.9827561,0.00004223371,0.000092201,0.004840305],"study_design_scores_gemma":[0.00002693036,0.0009532899,0.1420085,0.00006368768,0.0001676426,0.02612843,0.0004027426,0.001600438,0.824798,0.00009342085,0.003722209,0.00003458036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955509,0.002070732,0.001103724,0.0002083992,0.00001791609,0.00005016227,0.0004133834,0.00005100793,0.0005338351],"genre_scores_gemma":[0.9964787,0.0009607945,0.001613156,0.00007732185,0.00002453465,0.00002078281,0.0006026701,0.000008821379,0.0002131987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001465247,"threshold_uncertainty_score":0.002913475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01557066934038429,"score_gpt":0.3040420866056769,"score_spread":0.2884714172652927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}