{"id":"W2148856726","doi":"10.1128/aac.44.1.30-38.2000","title":"Efficacies of Topical Formulations of Foscarnet and Acyclovir and of 5-Percent Acyclovir Ointment (Zovirax) in a Murine Model of Cutaneous Herpes Simplex Virus Type 1 Infection","year":2000,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Foscarnet; Aciclovir; Herpes simplex virus; Virology; Medicine; Valaciclovir; Simplexvirus; Alphaherpesvirinae; Virus; Herpesviridae; Viral disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004082277,0.0005586434,0.0004889232,0.000549464,0.0001631142,0.0002849414,0.0002398339,0.0004743128,0.000933176],"category_scores_gemma":[0.0003857632,0.0002194937,0.000269361,0.0001887911,0.0002927107,0.000439739,0.0001284682,0.0005371187,0.000152576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002681694,"about_ca_system_score_gemma":0.0002460721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005199086,"about_ca_topic_score_gemma":0.0008976189,"domain_scores_codex":[0.9995525,0.0001013165,0.00002796226,0.00006390653,0.0001552558,0.00009893573],"domain_scores_gemma":[0.9997,0.00009132472,0.00007768617,0.0000194768,0.00003559152,0.00007597406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001041817,0.0005898835,0.000333033,0.000114727,0.00002131515,0.0000475201,0.0000351478,0.0003194,0.9897112,0.00008521474,0.00004522162,0.007655465],"study_design_scores_gemma":[0.00008584835,0.02320118,0.003583962,0.00002103036,0.00006221945,0.0002348769,0.00003132546,0.000813562,0.9703887,0.00004076678,0.001524644,0.00001185525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923187,0.004854505,0.0009645893,0.00005092725,0.00006362284,0.00009198371,0.0001184521,0.00003885412,0.001498267],"genre_scores_gemma":[0.9934713,0.002646617,0.001900392,0.00002946997,0.00003994926,0.00006235533,0.0001315795,0.00001409227,0.001704399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000933176,"threshold_uncertainty_score":0.003121793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01893614684930873,"score_gpt":0.281647759334922,"score_spread":0.2627116124856133,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}