{"id":"W2148874440","doi":"10.1139/cjpp-2014-0394","title":"The CBS/CSE system: a potential therapeutic target in NAFLD?","year":2014,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada; University of Manitoba; St. Boniface Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cystathionine beta synthase; Fatty liver; Homocysteine; Medicine; Pathogenesis; Steatohepatitis; Liver disease; Diabetes mellitus; Metabolic disorder; Bioinformatics; Disease; Internal medicine; Endocrinology; Biology; Enzyme; Cysteine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008064457,0.0003682492,0.001210259,0.0002522888,0.0002403413,0.00001863621,0.0007398133,0.000778057,0.00007738037],"category_scores_gemma":[0.00005100478,0.0002511092,0.0003343525,0.0001226767,0.0006950579,0.000003739785,0.00007599393,0.0007879743,0.00001157782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009380649,"about_ca_system_score_gemma":0.001695567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001206682,"about_ca_topic_score_gemma":0.0006155628,"domain_scores_codex":[0.9966838,0.001524354,0.0007834492,0.0003543468,0.0000521679,0.0006018286],"domain_scores_gemma":[0.9984482,0.0002185748,0.0006487793,0.0002514781,0.0001199658,0.000313026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001245428,0.0002105263,0.0004091028,0.02086306,0.009067168,0.001685993,0.0003811595,0.0002588122,0.1954981,0.003061874,0.05985023,0.7074685],"study_design_scores_gemma":[0.0005084045,0.0004040313,0.000029457,0.0002330571,0.0003304773,0.001574371,0.00002603832,0.00001125545,0.0003603246,0.0002565801,0.9960219,0.0002441338],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003404696,0.992267,0.00003078977,0.0001202225,0.003754548,0.000282333,0.00002860775,0.000002614815,0.0001092536],"genre_scores_gemma":[0.08080166,0.9167361,0.00003634796,0.0004351786,0.001778663,0.00003374767,0.00004943824,0.0000391245,0.00008976049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9361717,"threshold_uncertainty_score":0.9999941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01644889777214541,"score_gpt":0.3002840189339407,"score_spread":0.2838351211617953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}