{"id":"W2148916486","doi":"10.1152/ajpheart.00936.2007","title":"The AMPK γ1 R70Q mutant regulates multiple metabolic and growth pathways in neonatal cardiac myocytes","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Heritage Medical Research Clinic; University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Glycogen synthase; AMPK; NFAT; GSK-3; Myocyte; Glycogen; Internal medicine; Endocrinology; Phosphorylation; Protein kinase A; GSK3B; Glycolysis; Biology; Chemistry; Cell biology; Calcineurin; Metabolism; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002360377,0.0005876259,0.000260916,0.000290349,0.0001501913,0.0002478014,0.0003543389,0.0003114464,0.001268448],"category_scores_gemma":[0.0002129436,0.0002206322,0.0002728894,0.0001491832,0.0004144732,0.0001652363,0.0002013777,0.0005240951,0.0004239237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003515039,"about_ca_system_score_gemma":0.0002253287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006223216,"about_ca_topic_score_gemma":0.0006533344,"domain_scores_codex":[0.9998049,0.00003677161,0.00003917794,0.00003865461,0.00004756086,0.0000329601],"domain_scores_gemma":[0.9997752,0.00004340338,0.00009745684,0.00002396332,0.00001358652,0.00004629175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001355214,0.00002259542,0.0001888647,0.00001323441,0.000004048584,0.00009863423,0.00001258509,0.00009347127,0.9989567,0.0000564313,0.0000172287,0.0004007032],"study_design_scores_gemma":[0.00007268081,0.0006886419,0.01418325,0.0000249776,0.00003706541,0.0008112087,0.0001244032,0.002490611,0.9805884,0.0001583114,0.0008057223,0.00001473958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977506,0.0003964886,0.001010614,0.00007074313,0.00001675321,0.0000146743,0.0002500543,0.00005068867,0.0004393633],"genre_scores_gemma":[0.9961094,0.0007038552,0.001325136,0.00009370001,0.000009970192,0.00005210886,0.0004129053,0.00004893321,0.001243952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001268448,"threshold_uncertainty_score":0.004243374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006315291109562944,"score_gpt":0.217751138575477,"score_spread":0.2114358474659141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}