{"id":"W2148930557","doi":"10.1101/gr.118414.110","title":"Estimation of rearrangement phylogeny for cancer genomes","year":2011,"lang":"en","type":"article","venue":"Genome Research","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Medical Research Council; Cancer Research UK; Wellcome Trust","keywords":"Biology; Genome; Computational biology; Genetics; Karyotype; Somatic cell; Gene rearrangement; Genomics; Evolutionary biology; Gene; Chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001268205,0.0004030007,0.0006905866,0.003852339,0.000606636,0.0009769505,0.0007070751,0.0006704505,0.001717263],"category_scores_gemma":[0.008285907,0.0004917629,0.0007045406,0.002710018,0.0004703825,0.001196794,0.0008487037,0.000869331,0.0004434342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001300169,"about_ca_system_score_gemma":0.0004752521,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003274669,"about_ca_topic_score_gemma":0.003101411,"domain_scores_codex":[0.9993696,0.0002248731,0.00003340656,0.0002298713,0.00008933761,0.00005295562],"domain_scores_gemma":[0.9978409,0.001315227,0.0003141446,0.0002642029,0.0001711392,0.00009428967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0003290547,0.00007127079,0.1397031,0.0002964204,0.0002166791,0.0003200814,0.0005576784,0.6532921,0.02960356,0.03485919,0.002083022,0.1386679],"study_design_scores_gemma":[0.00001165407,0.00005694959,0.03505163,0.00002865476,0.00002847519,0.0002994087,0.000135692,0.9368668,0.003164462,0.0206544,0.003673915,0.00002801127],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.4411223,0.001278608,0.5513418,0.0003241154,0.0000136544,0.00005990011,0.003242541,0.00102503,0.001592061],"genre_scores_gemma":[0.7097709,0.0008826137,0.2807176,0.00003756398,0.00002205717,0.0001029164,0.0075865,0.0002050363,0.0006747881],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.003852339,"threshold_uncertainty_score":0.009433448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.104520587350761,"score_gpt":0.3543059501946551,"score_spread":0.249785362843894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}