{"id":"W2148967786","doi":"10.1093/bioinformatics/btp431","title":"Path: a tool to facilitate pathway-based genetic association analysis","year":2009,"lang":"en","type":"article","venue":"Bioinformatics","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"dbSNP; Single-nucleotide polymorphism; SNP; KEGG; Genome browser; OMIM : Online Mendelian Inheritance in Man; Genetic association; Tag SNP; Genome-wide association study; Computational biology; Computer science; Biology; Genetics; Genome; Genomics; Gene; Genotype; Gene ontology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00422034,0.00190402,0.001328852,0.003812268,0.0008492603,0.002166069,0.002758344,0.001077581,0.07287227],"category_scores_gemma":[0.01318316,0.001421208,0.002087953,0.003067561,0.0006637615,0.002060809,0.004309416,0.002052602,0.01761158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007564148,"about_ca_system_score_gemma":0.003084833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002841252,"about_ca_topic_score_gemma":0.004303195,"domain_scores_codex":[0.9988298,0.0003935968,0.0001407046,0.0002816978,0.0002704438,0.00008373116],"domain_scores_gemma":[0.9923765,0.005959536,0.0003992208,0.0005054017,0.0004656631,0.0002937475],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00187794,0.0002764794,0.01357423,0.005716479,0.001329509,0.002190199,0.0009540063,0.01602286,0.008264681,0.03035198,0.6823678,0.2370738],"study_design_scores_gemma":[0.00224017,0.0002853479,0.01099423,0.001119894,0.0006915399,0.002822943,0.0003705485,0.1558591,0.01322053,0.1476719,0.6643487,0.000375097],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"methods","genre_gemma":"software","genre_scores_codex":[0.004796984,0.0006171801,0.5890896,0.001170999,0.0003472209,0.0007470454,0.08580778,0.3122272,0.005195935],"genre_scores_gemma":[0.04358143,0.00145178,0.8135265,0.001211069,0.0001609215,0.004822113,0.09480391,0.03328436,0.007158025],"genre_candidate":"software","genre_consensus":null,"teacher_disagreement_score":0.07287227,"threshold_uncertainty_score":0.243782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703015430497577,"score_gpt":0.2398785045439399,"score_spread":0.2228483502389641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}