{"id":"W2148977592","doi":"10.1038/ng.3226","title":"A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome","year":2015,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":129,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"Wellcome Trust; National Eye Institute; Howard Hughes Medical Institute","keywords":"Biology; Genetics; Computational biology; Bioinformatics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002444688,0.0002693491,0.0002729423,0.0001572283,0.000126039,0.0001054418,0.0004352623,0.0001691099,0.00002625689],"category_scores_gemma":[0.001535909,0.0002439538,0.00004943091,0.001037172,0.00004639075,0.00005138953,0.0001887311,0.0003499994,0.000112644],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001958385,"about_ca_system_score_gemma":0.0001976803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001807199,"about_ca_topic_score_gemma":0.0001690074,"domain_scores_codex":[0.9973764,0.0002788859,0.0002665553,0.0008083395,0.0008169816,0.0004528698],"domain_scores_gemma":[0.9982256,0.0001144862,0.0001052438,0.0006627355,0.0003173759,0.0005745749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004127059,0.001206098,0.1225844,0.00006321992,0.00006254527,0.0009948267,0.007741653,0.02045351,0.8104513,0.000333947,0.03380883,0.001886986],"study_design_scores_gemma":[0.001080907,0.001397985,0.3494072,0.00009315822,0.00005696541,0.0001362554,0.0001710472,0.001053712,0.6418449,0.0006834143,0.003323092,0.0007514023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958248,0.00006703093,0.0008837736,0.001309848,0.0003685199,0.0008502517,0.0001689458,0.0001046585,0.0004221633],"genre_scores_gemma":[0.9872814,0.000002843361,0.002175861,0.01005738,0.00006449951,0.00003954099,0.00001256456,0.00004415182,0.0003217852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2268228,"threshold_uncertainty_score":0.9948146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04280905464532408,"score_gpt":0.2881270169217583,"score_spread":0.2453179622764342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}