{"id":"W2149146665","doi":"10.1016/j.imbio.2011.07.007","title":"CD40-mediated cell death requires TRAF6 recruitment","year":2011,"lang":"en","type":"article","venue":"Immunobiology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research","keywords":"Programmed cell death; CD40; Cell biology; Intracellular; Apoptosis; Biology; Caspase; Effector; Cell growth; Cancer research; Cytotoxic T cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002582454,0.0006124382,0.0002616,0.0002915474,0.0004694311,0.000697228,0.0002915287,0.0006179431,0.004674647],"category_scores_gemma":[0.0002049742,0.0001931203,0.0005245103,0.0002142453,0.0003157516,0.0005814207,0.000410808,0.001196319,0.00191822],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008931145,"about_ca_system_score_gemma":0.000313962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004365534,"about_ca_topic_score_gemma":0.0005115886,"domain_scores_codex":[0.999689,0.00003192657,0.00002131828,0.00005497892,0.00008454928,0.0001183124],"domain_scores_gemma":[0.9998245,0.00002111744,0.00003622153,0.00003385736,0.00002691242,0.00005744531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001641661,0.00001743466,0.00009510358,0.00004165361,0.000005265527,0.0001275579,0.00001180938,0.00002780005,0.9980279,0.000436484,0.00007759856,0.0009672335],"study_design_scores_gemma":[0.00001396719,0.00005368369,0.002643219,0.000005404587,0.000005693496,0.0007382103,0.0000228197,0.0002540356,0.9929914,0.0002385859,0.003028746,0.00000426515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9653823,0.006241588,0.01306735,0.0007723591,0.0002404111,0.00009595755,0.001826657,0.0005402892,0.0118331],"genre_scores_gemma":[0.9848292,0.001422119,0.003037333,0.000107694,0.00003229427,0.00004407235,0.001131733,0.00003299082,0.009362574],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004674647,"threshold_uncertainty_score":0.01563823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08896778882592114,"score_gpt":0.2717567198443572,"score_spread":0.182788931018436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}