{"id":"W2149148435","doi":"10.1101/gad.889201","title":"Suppression of cap-dependent translation in mitosis","year":2001,"lang":"en","type":"article","venue":"Genes & Development","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":227,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Cancer Institute; Howard Hughes Medical Institute","keywords":"EIF4E; EIF4G; Mitosis; Biology; Cell biology; eIF4A; Eukaryotic translation; EIF4A1; Translation (biology); Messenger RNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011228,0.0003485057,0.0003979125,0.0002285655,0.0002010833,0.0003459926,0.0001999141,0.0002372054,0.001047569],"category_scores_gemma":[0.0001232101,0.0001760955,0.0002102348,0.0001355822,0.0002273323,0.0002058912,0.0002428253,0.0004921861,0.0003852632],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003958053,"about_ca_system_score_gemma":0.0002280342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005358352,"about_ca_topic_score_gemma":0.0007725172,"domain_scores_codex":[0.9998999,0.00001355283,0.0000151731,0.00002474043,0.0000243261,0.00002240261],"domain_scores_gemma":[0.9998709,0.00002330284,0.00004450282,0.00001754141,0.00001289791,0.00003093933],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001007441,0.00001365314,0.0001494757,0.0000410087,0.000003077868,0.000040699,0.00000553438,0.00005168007,0.9980025,0.0001577616,0.00003656821,0.001397314],"study_design_scores_gemma":[0.00001737262,0.0001781044,0.00527703,0.000007062968,0.00000896604,0.0002685511,0.00001007519,0.000445039,0.9906278,0.0001032474,0.00305281,0.000004011965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878386,0.005402532,0.003615152,0.000169176,0.00008711726,0.00002959361,0.000441345,0.0001902028,0.002226216],"genre_scores_gemma":[0.9920886,0.002061312,0.00250561,0.00008818096,0.00002380231,0.00003588045,0.0008197423,0.00003034454,0.002346524],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001047569,"threshold_uncertainty_score":0.003504515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01884849076922471,"score_gpt":0.2620895536596502,"score_spread":0.2432410628904255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}