{"id":"W2149187834","doi":"10.1042/bj20031219","title":"Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene","year":2004,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"melanin and skin pigmentation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Gene; Exon; Biology; Intron; Mutant; Coding region; Molecular biology; Chinese hamster ovary cell; Genetics; Promoter; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096712,0.0004325966,0.0002160075,0.0003575653,0.0002040527,0.0002295397,0.0004661517,0.0002613963,0.0008494427],"category_scores_gemma":[0.0001217707,0.0003152253,0.0004977095,0.0002557912,0.0002912492,0.0001381294,0.000371732,0.0005496565,0.0006967258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004109212,"about_ca_system_score_gemma":0.0003930928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287371,"about_ca_topic_score_gemma":0.00131614,"domain_scores_codex":[0.9998467,0.00001562921,0.00001790962,0.00004887523,0.0000398959,0.00003093719],"domain_scores_gemma":[0.9998111,0.00003699099,0.00005588313,0.00003345927,0.00001519999,0.00004731744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004950691,0.00001356305,0.0001913377,0.00001383778,0.000003331911,0.00004281464,0.00001685121,0.00004206918,0.9988188,0.00008642513,0.000009758592,0.0007116823],"study_design_scores_gemma":[0.00004835128,0.0001932913,0.01347839,0.0000159245,0.00006871513,0.0005666995,0.00004713484,0.001485837,0.9790787,0.0001265733,0.004877668,0.00001277637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875474,0.000798142,0.009694351,0.00005123928,0.0000303804,0.00006300634,0.0008323443,0.0001611585,0.0008219877],"genre_scores_gemma":[0.9833907,0.0005791835,0.00910779,0.0000355773,0.00001110183,0.0001006836,0.003469766,0.00006063822,0.003244514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001287371,"threshold_uncertainty_score":0.002981424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003853252229627077,"score_gpt":0.2101391207399058,"score_spread":0.2062858685102787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}