{"id":"W2149258023","doi":"10.1086/505393","title":"A Randomized, Open-Label, Multicenter Comparative Study of the Efficacy and Safety of Piperacillin-Tazobactam and Cefepime for the Empirical Treatment of Febrile Neutropenic Episodes in Patients with Hematologic Malignancies","year":2006,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Hôpital Maisonneuve-Rosemont; University of Manitoba; McMaster University; CancerCare Manitoba","funders":"Pfizer Canada; Astellas Pharma; Enzon Pharmaceuticals; Pfizer; Amgen","keywords":"Cefepime; Piperacillin/tazobactam; Medicine; Febrile neutropenia; Piperacillin; Tazobactam; Internal medicine; Odds ratio; Clinical endpoint; Randomized controlled trial; Neutropenia; Surgery; Antibiotics; Chemotherapy; Antibiotic resistance; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007070106,0.00209212,0.003629023,0.000678175,0.0007469638,0.001463265,0.001445314,0.002904725,0.005605075],"category_scores_gemma":[0.009809585,0.001213045,0.002152987,0.0006024592,0.003019536,0.002121486,0.0007419342,0.002780825,0.0008299684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001228797,"about_ca_system_score_gemma":0.002412464,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009292256,"about_ca_topic_score_gemma":0.001732464,"domain_scores_codex":[0.9944745,0.003990455,0.0003689079,0.0005619308,0.0002755433,0.0003286816],"domain_scores_gemma":[0.9912088,0.0036061,0.00216764,0.000759174,0.0005904629,0.001667808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9802436,0.01309095,0.0007901274,0.0001463785,0.0004459803,0.00001823357,0.00004357992,0.0001104115,0.0009883142,0.0000454792,0.0001245735,0.00395222],"study_design_scores_gemma":[0.8921914,0.1061065,0.0009531692,0.00001057502,0.0001828721,0.000013632,0.00001760465,0.0002077255,0.000160175,0.00003673783,0.0001115174,0.000008127844],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930402,0.001287209,0.0005669117,0.0003122027,0.0003696537,0.003579451,0.000328842,0.00003953772,0.0004758365],"genre_scores_gemma":[0.9896549,0.0008359284,0.002100021,0.0007004084,0.000824855,0.004626384,0.0005505275,0.00001385478,0.0006930614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007070106,"threshold_uncertainty_score":0.03739077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1118281684125291,"score_gpt":0.4051004941023321,"score_spread":0.2932723256898029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}