{"id":"W2149258023","doi":"10.1086/505393","title":"A Randomized, Open-Label, Multicenter Comparative Study of the Efficacy and Safety of Piperacillin-Tazobactam and Cefepime for the Empirical Treatment of Febrile Neutropenic Episodes in Patients with Hematologic Malignancies","year":2006,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Neutropenia and Cancer Infections","field":"Medicine","cited_by":125,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Hôpital Maisonneuve-Rosemont; University of Manitoba; McMaster University; CancerCare Manitoba","funders":"Pfizer Canada; Astellas Pharma; Enzon Pharmaceuticals; Pfizer; Amgen","keywords":"Cefepime; Piperacillin/tazobactam; Medicine; Febrile neutropenia; Piperacillin; Tazobactam; Internal medicine; Odds ratio; Clinical endpoint; Randomized controlled trial; Neutropenia; Surgery; Antibiotics; Chemotherapy; Antibiotic resistance; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002058885,0.0001795052,0.001250182,0.00004176896,0.0001198784,0.00001630319,0.00009260658,0.00004729873,0.00001018605],"category_scores_gemma":[0.0002291438,0.00008078754,0.0001279939,0.0001762035,0.0007831167,0.00006234141,0.0000890783,0.00008019178,2.633558e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003504378,"about_ca_system_score_gemma":0.00007884471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004514056,"about_ca_topic_score_gemma":0.0006789737,"domain_scores_codex":[0.9981919,0.0004058901,0.0008467693,0.0002779037,0.0001365525,0.0001409813],"domain_scores_gemma":[0.9956242,0.003407653,0.0004035961,0.0002939227,0.0002071699,0.00006341864],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04051919,0.01743547,0.9408144,0.00005982344,0.0003538926,8.76509e-7,0.0003359524,0.00006158432,0.00001299592,0.00005564522,0.00003650417,0.0003136785],"study_design_scores_gemma":[0.2478611,0.004980251,0.7455849,0.0001013268,0.0009863516,0.000001411063,0.0002194561,0.00006339819,0.00006881185,0.00003303041,0.00003450283,0.00006546003],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928265,0.0006089027,0.00001451385,0.0001064165,0.00007092497,0.006220753,0.00007113745,0.000009361667,0.0000714401],"genre_scores_gemma":[0.9993263,0.0001837036,0.00001170734,0.0000601704,0.00002451697,0.0003490007,0.000008199342,0.00001054534,0.00002587805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2073419,"threshold_uncertainty_score":0.329442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1118281684125291,"score_gpt":0.4051004941023321,"score_spread":0.2932723256898029,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}