{"id":"W2149332737","doi":"10.1002/ijc.29829","title":"Genomic hallmarks of homologous recombination deficiency in invasive breast carcinomas","year":2015,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Breast cancer; Cancer research; Oncology; Biomarker; Cisplatin; SNP; Internal medicine; Biology; Medicine; Cancer; Gene; Chemotherapy; Genotype; Single-nucleotide polymorphism; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002742566,0.00006342657,0.0001098552,0.0001322097,0.000005234281,0.000008267315,0.000290666,0.00006223976,0.00002529154],"category_scores_gemma":[0.00009224073,0.00005991022,0.00006761124,0.00004348335,0.00003070151,0.000009685559,0.00006180425,0.00007211039,0.000001312835],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001456494,"about_ca_system_score_gemma":0.0004318883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001213607,"about_ca_topic_score_gemma":0.0002963892,"domain_scores_codex":[0.9992297,0.00003993156,0.0003128971,0.00009332471,0.0002437205,0.00008036759],"domain_scores_gemma":[0.9988688,0.00000980357,0.0003214708,0.00007366495,0.000679369,0.00004686359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006477975,0.0002200417,0.1091064,0.00001116286,0.0001596488,0.00007798366,0.0003492006,0.002345594,0.8720353,0.0005346394,0.001133356,0.01337884],"study_design_scores_gemma":[0.005241556,0.001021316,0.2022169,0.0001809222,0.00005189402,0.001469131,0.00048411,0.0001877436,0.7810512,0.005555471,0.002241971,0.0002977855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958383,0.001701329,0.0003319055,0.0003187202,0.0008716621,0.00004546088,0.00001538649,0.000001148503,0.0008760222],"genre_scores_gemma":[0.9990265,0.000208759,0.0003792987,0.00008072156,0.0001735531,0.000003432975,0.000007772858,0.000007900855,0.0001120741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09311051,"threshold_uncertainty_score":0.2443068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01362812140811927,"score_gpt":0.2767785132426678,"score_spread":0.2631503918345485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}