{"id":"W2149400959","doi":"10.1158/0008-5472.can-08-2657","title":"Cancer-Specific Transgene Expression Mediated by Systemic Injection of Nanoparticles","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Medical Research Council; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; National Cancer Institute; Institut National Du Cancer; Cancer Research UK; Association pour la Recherche sur le Cancer; Ohio State University","keywords":"Transgene; Cancer; Cancer research; Biology; Medicine; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002550342,0.00009035425,0.0001246801,0.00006665679,0.00007457632,0.0000151402,0.0002110785,0.0001171833,0.00009066945],"category_scores_gemma":[0.00001883296,0.00007962232,0.00004620005,0.0002031818,0.00008237459,0.000006099926,0.00002638635,0.0001210179,0.000008506088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004501279,"about_ca_system_score_gemma":0.0001151892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001333133,"about_ca_topic_score_gemma":0.00004045862,"domain_scores_codex":[0.9988488,0.0001196453,0.0001945987,0.0002850546,0.0002721162,0.0002797858],"domain_scores_gemma":[0.9993727,0.00001258119,0.00004457997,0.0002357104,0.0002571693,0.00007722561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002557123,0.000044158,0.0004999661,0.00002194237,0.00001356694,8.657838e-7,0.0001016819,0.00008879882,0.967553,0.000003183237,0.02481984,0.00659729],"study_design_scores_gemma":[0.0003218276,0.0004730448,0.000459857,0.0001152754,0.000002956271,0.0000033189,0.0001437288,0.00001152958,0.9934628,0.00001791223,0.004900394,0.00008735008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9780536,0.02115944,0.00009979706,0.0001974109,0.000109473,0.0001734266,0.0000644781,0.000008369976,0.0001340344],"genre_scores_gemma":[0.9883536,0.01087927,0.00001031424,0.0000430322,0.0001580774,0.00007422244,0.0000455195,0.00001048069,0.0004255196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02590981,"threshold_uncertainty_score":0.3246904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04504925699305366,"score_gpt":0.3570249915789128,"score_spread":0.3119757345858591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}