{"id":"W2149400959","doi":"10.1158/0008-5472.can-08-2657","title":"Cancer-Specific Transgene Expression Mediated by Systemic Injection of Nanoparticles","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotel Dieu Hospital","funders":"Medical Research Council; Ligue Contre le Cancer; Institut National de la Santé et de la Recherche Médicale; National Cancer Institute; Institut National Du Cancer; Cancer Research UK; Association pour la Recherche sur le Cancer; Ohio State University","keywords":"Transgene; Cancer; Cancer research; Biology; Medicine; Internal medicine; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002327607,0.0004770469,0.0004252622,0.0003033277,0.0001237897,0.0003087667,0.0002321656,0.000439042,0.0009041572],"category_scores_gemma":[0.0001420196,0.0001710513,0.0002513336,0.0001521866,0.0003494429,0.0002371328,0.00026426,0.0005465627,0.0004607607],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002940982,"about_ca_system_score_gemma":0.0002998064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003603313,"about_ca_topic_score_gemma":0.0005440403,"domain_scores_codex":[0.9998179,0.00002283873,0.00001149624,0.00007931265,0.00004262989,0.00002583807],"domain_scores_gemma":[0.9999193,0.00001499039,0.00002192657,0.00001864374,0.00001362864,0.00001148925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003148785,0.00001617355,0.0000509672,0.00003521494,0.000003786753,0.00003348652,0.00001438365,0.00005601598,0.9973825,0.0001914414,0.00007055428,0.00211402],"study_design_scores_gemma":[0.00001040206,0.0001971307,0.0003149325,0.000004541481,0.00001416928,0.0001577597,0.000004601224,0.0008632321,0.9945924,0.00004762916,0.003789306,0.000003841898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8560076,0.00531231,0.1247901,0.0005069654,0.0002243476,0.0004781395,0.0008732541,0.002242198,0.009564999],"genre_scores_gemma":[0.9467097,0.002873273,0.03981702,0.0001498511,0.00005164695,0.0003320189,0.0008056337,0.0002150865,0.009045772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009041572,"threshold_uncertainty_score":0.003024638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04504925699305366,"score_gpt":0.3570249915789128,"score_spread":0.3119757345858591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}