{"id":"W2149429471","doi":"10.1128/jb.00198-08","title":"The<i>Francisella</i>Pathogenicity Island Protein PdpD Is Required for Full Virulence and Associates with Homologues of the Type VI Secretion System","year":2008,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Francisella tularensis; Francisella; Tularemia; Biology; Virulence; Pathogenicity island; Secretion; Microbiology; Gene; Intracellular parasite; Intracellular; Genetics; Bacterial outer membrane; Pathogen; Escherichia coli; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006916113,0.000273929,0.0002115983,0.0001730679,0.0001705267,0.0002803253,0.0001923993,0.0002468339,0.0004322655],"category_scores_gemma":[0.0001552739,0.0001132945,0.000210875,0.0001279578,0.0001775294,0.0002215475,0.0003067647,0.0003315823,0.0004458451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003232931,"about_ca_system_score_gemma":0.000194361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001920147,"about_ca_topic_score_gemma":0.001639532,"domain_scores_codex":[0.9998819,0.00001517793,0.00001035074,0.00002076222,0.000036505,0.00003529289],"domain_scores_gemma":[0.9998533,0.00002640287,0.00005014485,0.00001724305,0.00001987925,0.00003297901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002396426,0.000008357248,0.0002972056,0.00001221656,0.000001161127,0.00004868577,0.000008093173,0.00001423017,0.9990293,0.00004997783,0.00002771808,0.0004791721],"study_design_scores_gemma":[0.000007298042,0.00007169534,0.02824434,0.00001010108,0.00001200613,0.0009361061,0.00005716138,0.0009720859,0.9653647,0.00008255617,0.004234019,0.000007950218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922133,0.001253361,0.004652608,0.0001231358,0.00002271427,0.00001143274,0.0003208556,0.0001096158,0.001292976],"genre_scores_gemma":[0.9963053,0.0002349043,0.001563322,0.00004024342,0.000007241437,0.00001045292,0.0008604104,0.00003067079,0.0009474228],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001920147,"threshold_uncertainty_score":0.003817976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01234929668001357,"score_gpt":0.2311938798530518,"score_spread":0.2188445831730383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}