{"id":"W2149429471","doi":"10.1128/jb.00198-08","title":"The<i>Francisella</i>Pathogenicity Island Protein PdpD Is Required for Full Virulence and Associates with Homologues of the Type VI Secretion System","year":2008,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Francisella tularensis; Francisella; Tularemia; Biology; Virulence; Pathogenicity island; Secretion; Microbiology; Gene; Intracellular parasite; Intracellular; Genetics; Bacterial outer membrane; Pathogen; Escherichia coli; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006107545,0.0001179464,0.0002766544,0.00002356825,0.0002236193,0.00001428678,0.0002431122,0.0001731019,0.000003713578],"category_scores_gemma":[0.0002074566,0.00006201824,0.0001054775,0.00007242521,0.0003695422,0.000007537578,0.00006987534,0.0001263908,6.278101e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002075206,"about_ca_system_score_gemma":0.0001699399,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001268217,"about_ca_topic_score_gemma":0.00004581383,"domain_scores_codex":[0.9989433,0.0001955965,0.0003581139,0.0001548331,0.0001293782,0.0002188045],"domain_scores_gemma":[0.998675,0.00006505958,0.0004832602,0.0002038168,0.000519251,0.00005361204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002095671,0.00001987529,0.004145776,0.00004775109,0.00008939682,0.00000338916,0.00009173823,0.000001873253,0.9928264,0.00003035367,0.000211142,0.0004366034],"study_design_scores_gemma":[0.005923032,0.01762295,0.1243284,0.0004040216,0.0001856905,0.003272055,0.0004207262,0.0002571936,0.8057257,0.0004285515,0.04081107,0.0006205993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975198,0.001190861,0.0004446585,0.0002282384,0.0002158018,0.0003000812,0.00005251803,0.000001858492,0.00004621414],"genre_scores_gemma":[0.9985874,0.0007508685,0.0002180646,0.0000392539,0.0002188799,0.00001000604,0.000006439297,0.00001195089,0.0001571259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1871008,"threshold_uncertainty_score":0.252903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01234929668001357,"score_gpt":0.2311938798530518,"score_spread":0.2188445831730383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}