{"id":"W2149439920","doi":"10.1139/o03-046","title":"The complex interactions of p53 with target DNA: we learn as we go","year":2003,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Deutsche Krebshilfe; Deutsche Forschungsgemeinschaft","keywords":"Transactivation; Chromatin; DNA; Biology; DNA damage; Transcription factor; Gene; DNA repair; Context (archaeology); Cell biology; Computational biology; Function (biology); Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009147581,0.0002941838,0.0008387649,0.00003413759,0.00008899856,0.000007364829,0.0001239053,0.0004124199,0.0002334874],"category_scores_gemma":[0.00003511644,0.0001762873,0.0002061827,0.0001443209,0.0003924054,0.000005751879,0.00005270668,0.0005303652,0.00003094022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005903675,"about_ca_system_score_gemma":0.0004172489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006980807,"about_ca_topic_score_gemma":0.000001848924,"domain_scores_codex":[0.998888,0.0000876026,0.0003560247,0.0003721015,0.00006620078,0.0002300491],"domain_scores_gemma":[0.998978,0.000122401,0.0003136777,0.000421057,0.00006172343,0.0001031953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003208819,0.0004023431,0.00001307029,0.0328646,0.001581001,0.0001038085,0.00008670001,7.358199e-7,0.1334828,0.0003005583,0.0193547,0.8114889],"study_design_scores_gemma":[0.0003445388,0.0002251998,1.376764e-7,0.002065058,0.0005290923,0.0005312237,0.00005511431,9.772374e-7,0.01928255,0.00001959311,0.976778,0.0001684746],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001265011,0.9755008,0.0000240011,0.0001839653,0.0001459759,0.0003129365,0.00007315339,0.00001723902,0.02361549],"genre_scores_gemma":[0.0005141311,0.9902773,0.000138009,0.0000435649,0.0001089297,0.00004278673,0.0004008475,0.00002875153,0.008445701],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9574233,"threshold_uncertainty_score":0.7188787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02957024043517676,"score_gpt":0.3027131312403019,"score_spread":0.2731428908051252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}