{"id":"W2149517449","doi":"10.1021/bp0498084","title":"Production and Glycosylation of Recombinant β-Interferon in Suspension and Cytopore Microcarrier Cultures of CHO Cells","year":2005,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Microcarrier; Recombinant DNA; Bioprocess; Cell culture; Glycosylation; Chinese hamster ovary cell; Chemistry; Suspension culture; Biology; Cell biology; Biochemistry; Cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003942096,0.0005110187,0.0005398703,0.0003446282,0.0001897221,0.0005033337,0.0004189562,0.0004915164,0.00041706],"category_scores_gemma":[0.0003677893,0.0002444411,0.0004410477,0.0004708181,0.0002285363,0.0003137881,0.0003122932,0.0009894996,0.0004719208],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004804039,"about_ca_system_score_gemma":0.0001971239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001060923,"about_ca_topic_score_gemma":0.0009147675,"domain_scores_codex":[0.9996527,0.00006569957,0.00004338611,0.00008331105,0.0001107091,0.00004419893],"domain_scores_gemma":[0.9997993,0.00003830161,0.00003733832,0.00005062567,0.00005472765,0.00001980281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003097576,0.000008544965,0.0000389553,0.00001550682,0.000003189843,0.0000225324,0.00001429014,0.00004540381,0.9992694,0.00002980643,0.00001416852,0.0005071793],"study_design_scores_gemma":[0.00001130952,0.000158824,0.001115733,0.000006566043,0.00001596423,0.0001243658,0.00001743267,0.0008772869,0.9960808,0.00002858842,0.001557499,0.000005735854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9616852,0.002873801,0.03059354,0.0001315907,0.0001174872,0.0003038356,0.001413279,0.0002035949,0.002677559],"genre_scores_gemma":[0.907649,0.003112011,0.07394911,0.0001415406,0.00006109639,0.0004719067,0.006250774,0.0001575678,0.00820693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001060923,"threshold_uncertainty_score":0.00348556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005174838181956331,"score_gpt":0.2478066528167512,"score_spread":0.2426318146347949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}