{"id":"W2149518639","doi":"10.1080/07391102.2000.10506641","title":"DNA Sequence Recognition of a Cross-Linked Polyamide: CD Studies, Footprinting and Effects on the Activity of DNA Gyrase","year":2000,"lang":"en","type":"article","venue":"Journal of Biomolecular Structure and Dynamics","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Brandenburger Staatsministerium für Wissenschaft, Forschung und Kultur","keywords":"Footprinting; Dimer; Chemistry; Netropsin; DNA; Stereochemistry; Linker; Circular dichroism; Monomer; Binding site; DNA gyrase; DNA footprinting; Base pair; Deoxyribonuclease I; Crystallography; Biochemistry; DNA-binding protein; Minor groove; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805366,0.0001484595,0.0002457713,0.00003295086,0.00006301647,0.00001781213,0.0001175,0.0001482644,0.00000429935],"category_scores_gemma":[0.0001616872,0.0001038778,0.00009609555,0.00007860344,0.0002586271,0.000008316748,0.00005193207,0.0001529332,5.980006e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001501245,"about_ca_system_score_gemma":0.00003947998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005001479,"about_ca_topic_score_gemma":0.000004383566,"domain_scores_codex":[0.9992237,0.00005935324,0.0002745532,0.0001612673,0.0001557407,0.0001253715],"domain_scores_gemma":[0.9992095,0.00005119779,0.00034297,0.0001794321,0.000159662,0.00005727435],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002627668,0.00002209987,0.0009508909,0.000138127,0.0001656309,0.00001724696,0.00005034147,0.000005680437,0.9454518,0.00001880743,0.000008324197,0.05290827],"study_design_scores_gemma":[0.0006455075,0.0004469668,0.005349101,0.0001287821,0.00007617009,0.0001993826,0.00005340651,0.00010416,0.9920549,0.0007768067,0.00005076013,0.0001139906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986471,0.000835614,0.0001521904,0.0001189718,0.00005576009,0.00008068798,0.000033009,0.000001800754,0.00007485606],"genre_scores_gemma":[0.9987403,0.0006750855,0.0003649499,0.000110804,0.00007307265,6.338432e-7,0.000007294576,0.00001179169,0.0000160646],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05279428,"threshold_uncertainty_score":0.4236013,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01093875889051492,"score_gpt":0.2744994765483493,"score_spread":0.2635607176578344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}