{"id":"W2149529467","doi":"10.1128/aac.01664-10","title":"Effect of Antibiotic Treatment on the Intestinal Metabolome","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":275,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Foreign Affairs and International Trade Canada; University of British Columbia; Crohn's and Colitis Foundation of Canada; Genome British Columbia; Crohn's and Colitis Foundation; Canadian Institutes of Health Research; Genome Canada; Howard Hughes Medical Institute","keywords":"Metabolome; Biology; Metabolomics; Gut flora; Host (biology); Antibiotics; Homeostasis; Computational biology; Bioinformatics; Microbiology; Cell biology; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001263531,0.0001543346,0.0001736651,0.0000224821,0.00007168476,0.00000790397,0.0001017118,0.00006638913,0.00006804919],"category_scores_gemma":[0.000006653135,0.00008732278,0.00008213302,0.00004274003,0.0001059877,0.000001614678,0.00002198983,0.00004122216,0.000007816712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005436943,"about_ca_system_score_gemma":0.00001811623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007058109,"about_ca_topic_score_gemma":0.000005333267,"domain_scores_codex":[0.9993976,0.00006748215,0.0001286925,0.0002052819,0.00003517414,0.0001657575],"domain_scores_gemma":[0.9996634,0.00001374859,0.00006937555,0.0002031552,0.00001832574,0.00003203985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005664298,0.0002288774,0.01512258,0.00003823701,0.0001229662,0.000002069952,0.0002282417,2.294475e-7,0.9680343,0.00008816615,0.006076051,0.009491897],"study_design_scores_gemma":[0.0009472606,0.002610979,0.02721815,0.0000250771,0.00002739026,0.00001627815,0.000009055714,0.000002078965,0.9557258,0.00000410875,0.01331609,0.00009775983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998381,0.0000493236,0.00001680119,0.000370929,0.00006751347,0.0002371111,0.00001131533,0.00000538804,0.0008606729],"genre_scores_gemma":[0.9960233,0.0009873881,0.0001091454,0.00251387,0.00005586982,0.000002164564,0.00001491223,0.00001596287,0.0002774015],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01230848,"threshold_uncertainty_score":0.356092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832513649009476,"score_gpt":0.2636554613654566,"score_spread":0.2453303248753618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}