{"id":"W2149529467","doi":"10.1128/aac.01664-10","title":"Effect of Antibiotic Treatment on the Intestinal Metabolome","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":275,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Foreign Affairs and International Trade Canada; University of British Columbia; Crohn's and Colitis Foundation of Canada; Genome British Columbia; Crohn's and Colitis Foundation; Canadian Institutes of Health Research; Genome Canada; Howard Hughes Medical Institute","keywords":"Metabolome; Biology; Metabolomics; Gut flora; Host (biology); Antibiotics; Homeostasis; Computational biology; Bioinformatics; Microbiology; Cell biology; Genetics; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001854231,0.0002826502,0.0006578862,0.0002437496,0.0001568942,0.0003811126,0.0001115068,0.000424159,0.001781927],"category_scores_gemma":[0.0004863681,0.0001227253,0.0002221182,0.0002572406,0.0002212292,0.0001866453,0.0001770597,0.0004934036,0.0002446019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001797575,"about_ca_system_score_gemma":0.000227717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000675071,"about_ca_topic_score_gemma":0.001019083,"domain_scores_codex":[0.9997283,0.00009127088,0.00002174929,0.00004827523,0.00004427391,0.00006624892],"domain_scores_gemma":[0.9996427,0.0001387391,0.00006331781,0.00003540471,0.00004323986,0.0000765681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008765844,0.000309616,0.001981105,0.00009843918,0.00006087968,0.00009166506,0.00002712412,0.0001241752,0.9778956,0.00003020084,0.0002325126,0.01038286],"study_design_scores_gemma":[0.000176929,0.006775814,0.06487823,0.00002102542,0.0001446844,0.0003456393,0.0001251361,0.001627579,0.9209937,0.00009569305,0.004788863,0.00002651371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937602,0.003084551,0.0004364917,0.0003666215,0.000125948,0.0000347301,0.0008096663,0.00004773946,0.001334194],"genre_scores_gemma":[0.9959412,0.001147321,0.0007875796,0.0002178599,0.00002816063,0.00002476567,0.0007157009,0.00001961674,0.001117927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001781927,"threshold_uncertainty_score":0.00596118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832513649009476,"score_gpt":0.2636554613654566,"score_spread":0.2453303248753618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}