{"id":"W2149710067","doi":"10.1021/jo0491206","title":"Selective <i>tert</i>-Butyl Ester Deprotection in the Presence of Acid Labile Protecting Groups with Use of ZnBr<sub>2</sub>","year":2004,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Chemistry; Hydrolysis; Lewis acids and bases; Amino acid; Organic chemistry; Protecting group; Medicinal chemistry; Catalysis; Alkyl; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005468697,0.0001252966,0.0002134349,0.00001697788,0.0000512311,0.0000136343,0.0002809087,0.0001019597,0.000009087556],"category_scores_gemma":[0.0004128466,0.00006959347,0.0001074656,0.0002732303,0.0001111946,0.00001331711,0.00005858926,0.000324654,2.37034e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003476684,"about_ca_system_score_gemma":0.00009384283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000218769,"about_ca_topic_score_gemma":0.00003140048,"domain_scores_codex":[0.9990335,0.00008569009,0.0003733939,0.0001284665,0.0002367798,0.0001421331],"domain_scores_gemma":[0.9989516,0.00006364855,0.0005026149,0.0002713655,0.0001791737,0.0000316121],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002329404,0.000116281,0.0009318612,0.00005424124,0.00008473688,0.000002136342,0.0002953256,0.0002057174,0.9977108,2.094893e-7,0.000008820635,0.0003569472],"study_design_scores_gemma":[0.0004498964,0.0001535873,0.0007536422,0.0001242923,0.00008114728,0.0002113554,0.0004036968,0.000005734461,0.9976641,0.0000523169,0.00001748664,0.00008272762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976966,0.000194032,0.001781417,0.0001733423,0.000007795736,0.0001178198,0.000002761921,0.000001753436,0.00002447525],"genre_scores_gemma":[0.9995884,0.00009136664,0.0001653395,0.00002929313,0.00009976388,0.000004585339,0.000001594501,0.00001353516,0.000006110289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001891809,"threshold_uncertainty_score":0.2837939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0064198875498828,"score_gpt":0.1935032522150306,"score_spread":0.1870833646651478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}