{"id":"W2149736698","doi":"10.1093/carcin/bgu006","title":"Integrin α6A splice variant regulates proliferation and the Wnt/β-catenin pathway in human colorectal cancer cells","year":2014,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Wnt signaling pathway; Gene knockdown; Biology; Cancer research; Alternative splicing; Catenin; Integrin; Gene silencing; RNA splicing; Cell growth; Colorectal cancer; splice; RNA interference; Small interfering RNA; Cell biology; Cell culture; Messenger RNA; Molecular biology; Signal transduction; Cell; RNA; Cancer; Genetics; Gene; Transfection","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009436313,0.000171843,0.0002038829,0.0002656036,0.0001715032,0.0002849072,0.00008198396,0.0002269747,0.001626104],"category_scores_gemma":[0.0001254857,0.0001172518,0.0002862279,0.000251999,0.00009564529,0.00007140976,0.00008384943,0.0003802123,0.0005137231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001716344,"about_ca_system_score_gemma":0.000119775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125103,"about_ca_topic_score_gemma":0.001271131,"domain_scores_codex":[0.9998579,0.00002217828,0.00001535507,0.00002707171,0.00005038208,0.00002702713],"domain_scores_gemma":[0.9999444,0.000008358587,0.00001569096,0.000006931846,0.00001177766,0.00001276042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001543352,0.00002802173,0.000613679,0.00003192059,0.000008016968,0.0001108128,0.00001774205,0.00003828849,0.9975193,0.00005194136,0.00008286302,0.001343136],"study_design_scores_gemma":[0.00006630467,0.000922022,0.04869446,0.00001549351,0.00009496981,0.002027895,0.0001506636,0.002185852,0.9343541,0.0001064998,0.01136628,0.00001544124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931278,0.003379807,0.001058818,0.0001352085,0.00004485625,0.00002149018,0.000572462,0.00005207486,0.001607374],"genre_scores_gemma":[0.9939502,0.001630989,0.0008489557,0.00006226271,0.00001175689,0.00003093896,0.001058699,0.00001034668,0.002395828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001626104,"threshold_uncertainty_score":0.005439878,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01559238761186056,"score_gpt":0.2695152043444739,"score_spread":0.2539228167326134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}