{"id":"W2149744450","doi":"10.1261/rna.1923210","title":"Natural and artificial RNAs occupy the same restricted region of sequence space","year":2009,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"National Institute of General Medical Sciences","keywords":"Biology; Ribozyme; Computational biology; RNA; Sequence (biology); Complementarity (molecular biology); Genetics; Function (biology); Aptamer; Non-coding RNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007570585,0.00007303639,0.00007583328,0.00001478641,0.00005368971,0.00001239117,0.000110632,0.00007458116,0.000003204536],"category_scores_gemma":[0.000119968,0.00005056354,0.00003489519,0.00006049969,0.00005193266,0.000002286272,0.0000219479,0.00005339893,0.000001471943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003481209,"about_ca_system_score_gemma":0.00002707313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001820073,"about_ca_topic_score_gemma":0.000005547563,"domain_scores_codex":[0.9995174,0.00005026095,0.0001003949,0.0001449818,0.0000772332,0.0001097126],"domain_scores_gemma":[0.999642,0.000010573,0.00006723448,0.0002137457,0.00003355537,0.00003291817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007247626,0.000008400536,0.00001707733,0.000002629185,0.000006105411,0.000003649593,0.00002630736,0.000001643932,0.9770567,0.001446842,0.0003922468,0.02096591],"study_design_scores_gemma":[0.00006520056,0.0001688554,0.001280364,0.00001277516,0.000008068138,0.00002644614,0.00003095565,0.0000237108,0.9924481,0.00237584,0.00348596,0.00007373685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957283,0.001159939,0.000621671,0.001779661,0.00007999352,0.0001222548,0.000002741151,0.000007065042,0.0004983948],"genre_scores_gemma":[0.9985519,0.0002219201,0.0004515053,0.0002903741,0.0001210344,0.000002252546,0.000005630246,0.000004517049,0.0003508548],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02089217,"threshold_uncertainty_score":0.2061921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0213550207839403,"score_gpt":0.2573375840919072,"score_spread":0.2359825633079669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}