{"id":"W2149803755","doi":"10.1093/toxsci/kft087","title":"Serum Glutamate Dehydrogenase—Biomarker for Liver Cell Death or Mitochondrial Dysfunction?","year":2013,"lang":"en","type":"letter","venue":"Toxicological Sciences","topic":"Drug-Induced Hepatotoxicity and Protection","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Glutamate dehydrogenase; Mitochondrial DNA; Mitochondrion; Malate dehydrogenase; Biology; Purine nucleoside phosphorylase; Molecular biology; Riluzole; Pharmacology; Biochemistry; Glutamate receptor; Enzyme; Purine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007101709,0.001145066,0.002338781,0.001873203,0.0004230633,0.00214433,0.001502345,0.006169296,0.0009269848],"category_scores_gemma":[0.01583091,0.000314993,0.0006443157,0.0009052011,0.003407052,0.005026859,0.0008870321,0.007168895,0.001163955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008905245,"about_ca_system_score_gemma":0.0004963072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005598142,"about_ca_topic_score_gemma":0.0006411866,"domain_scores_codex":[0.997067,0.0009218622,0.0006848236,0.0005125304,0.0006440603,0.0001695725],"domain_scores_gemma":[0.9898528,0.004097365,0.0009431841,0.0003563527,0.004128036,0.000622243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003017758,0.0003039021,0.06734598,0.006476013,0.001351605,0.009798149,0.0008363066,0.0003914701,0.02148734,0.007985761,0.5158236,0.3651821],"study_design_scores_gemma":[0.0004105879,0.002627656,0.06520376,0.006516481,0.001618468,0.07574056,0.003661304,0.004022908,0.03546583,0.04881147,0.75517,0.0007509531],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.009636831,0.5306962,0.004435039,0.3870362,0.06693184,0.00004123777,0.000207948,0.0001165413,0.0008982218],"genre_scores_gemma":[0.1681402,0.2626868,0.007266931,0.2474142,0.308946,0.0001274706,0.0003809267,0.0001272503,0.004910243],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.007101709,"threshold_uncertainty_score":0.0375579,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3175662708489113,"score_gpt":0.4294016581907273,"score_spread":0.111835387341816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}