{"id":"W2149892146","doi":"10.1124/mol.105.020792","title":"Transactivation of Rat Apical Sodium-Dependent Bile Acid Transporter and Increased Bile Acid Transport by 1α,25-Dihydroxyvitamin D3 via the Vitamin D Receptor","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":80,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Calcitriol receptor; Bile acid; Symporter; Ileum; Internal medicine; Bile acid malabsorption; Endocrinology; Small intestine; Duodenum; Jejunum; Biology; Chemistry; Vitamin D and neurology; Biochemistry; Transporter; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004605459,0.0003986989,0.0006500654,0.0001709057,0.0001185084,0.000009639934,0.0002361291,0.0003221542,0.0008212503],"category_scores_gemma":[0.000002788695,0.0003004327,0.0002841407,0.0003083672,0.0002975093,0.000105159,0.000005227985,0.0004338641,0.00001053271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000565564,"about_ca_system_score_gemma":0.00009320725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001139923,"about_ca_topic_score_gemma":0.00004112663,"domain_scores_codex":[0.9974604,0.0002058204,0.0006839559,0.0005799307,0.0005636334,0.0005062839],"domain_scores_gemma":[0.9992169,0.00004962019,0.0001601445,0.0003026188,0.00009373814,0.0001769812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008964774,0.0009698972,0.0007454213,0.0002117028,0.0001590939,0.0003377271,0.0003823655,0.000007315545,0.99365,0.00008307511,0.001329876,0.001227096],"study_design_scores_gemma":[0.006062889,0.0004844033,0.002721997,0.00003353861,0.0008385259,0.00006991787,0.0001121833,0.00008105669,0.9806765,0.00008731974,0.008526351,0.0003052828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9494468,0.001002867,0.04563318,0.001728532,0.0004102902,0.001217993,0.0001209986,0.00007776985,0.000361549],"genre_scores_gemma":[0.9964488,0.0001047637,0.0006526174,0.001339173,0.0001405504,0.0001941148,0.0007004486,0.00006440546,0.0003551263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04700198,"threshold_uncertainty_score":0.9999448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003672950057177619,"score_gpt":0.2193393675701897,"score_spread":0.2156664175130121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}