{"id":"W2149893263","doi":"10.1128/jvi.02521-08","title":"Primary Occult Hepadnavirus Infection Induces Virus-Specific T-Cell and Aberrant Cytokine Responses in the Absence of Antiviral Antibody Reactivity in the Woodchuck Model of Hepatitis B Virus Infection","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Woodchuck hepatitis virus; Biology; Virology; Hepatitis B virus; Virus; Immunology; Antibody; Cytokine; Hepadnaviridae; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001282322,0.0003347477,0.0003137217,0.0002152326,0.0001346009,0.0002716478,0.000105161,0.0002463646,0.0007679537],"category_scores_gemma":[0.000192467,0.0001756276,0.0002005707,0.00009497718,0.0002620676,0.000232993,0.0001912186,0.0008862363,0.0002535844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001892525,"about_ca_system_score_gemma":0.0001893618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003343605,"about_ca_topic_score_gemma":0.0006920677,"domain_scores_codex":[0.9998294,0.00002160666,0.00001395316,0.00003723451,0.00002742724,0.00007041739],"domain_scores_gemma":[0.9998145,0.00003109026,0.00003911783,0.00003204986,0.00001912427,0.00006429346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005461866,0.0001946354,0.001924959,0.00005362783,0.000005118504,0.0001696774,0.00006749763,0.00006555492,0.9950565,0.00004602478,0.00002574945,0.001844392],"study_design_scores_gemma":[0.00009344354,0.01043788,0.09179714,0.00002806961,0.00005393341,0.001311312,0.0003709723,0.002138399,0.8920649,0.0002173985,0.001463974,0.00002260946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986969,0.0003700424,0.0003640619,0.00001368186,0.00001182345,0.00002539426,0.00005593441,0.00002882067,0.0004334801],"genre_scores_gemma":[0.9981035,0.0003196304,0.0003338011,0.00003009532,0.00001445825,0.00005322796,0.000164545,0.00000702257,0.000973584],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007679537,"threshold_uncertainty_score":0.00256902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03371522433039826,"score_gpt":0.3090116802748745,"score_spread":0.2752964559444762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}