{"id":"W2149923399","doi":"10.1126/science.1201954","title":"A Crystal Structure of the Complex Between Human Complement Receptor 2 and Its Ligand C3d","year":2011,"lang":"en","type":"article","venue":"Science","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Complement (music); Crystal structure; Ligand (biochemistry); Chemistry; Crystallography; Receptor; Computational biology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000185873,0.00008970881,0.0001488409,0.00005543527,0.0004383026,0.00001025469,0.0005575357,0.00002804274,0.001350107],"category_scores_gemma":[0.00003540153,0.00006001438,0.00002999272,0.0001879865,0.0008134273,0.00008641602,0.0003852143,0.00006788824,0.00001252062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001963103,"about_ca_system_score_gemma":0.00005294789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004299486,"about_ca_topic_score_gemma":0.00003746159,"domain_scores_codex":[0.999176,0.00007157872,0.0002141336,0.0002279431,0.00007827549,0.0002320265],"domain_scores_gemma":[0.999476,0.00002993205,0.0001319966,0.0002601706,0.00007628662,0.00002562804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00000478935,0.00001612008,0.07435354,0.00001545972,0.00001470622,5.812803e-8,0.0007668766,1.069099e-7,0.9225126,0.001819564,0.000422889,0.00007328438],"study_design_scores_gemma":[0.0003132081,0.00007635511,0.6104398,0.00002956261,0.00001616295,0.000003689833,0.0002728768,7.927754e-7,0.3851635,0.0003856656,0.00322313,0.0000752975],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983978,0.0002130173,0.000005070966,0.00004998409,0.0002030255,0.0002839672,0.0002837624,0.00001471406,0.0005486969],"genre_scores_gemma":[0.999786,0.000001119327,0.00005427606,0.00002721518,0.00001388675,0.000002659473,0.00001700694,0.000003508918,0.00009431901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5373492,"threshold_uncertainty_score":0.9995628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06515967091896947,"score_gpt":0.2940062839566217,"score_spread":0.2288466130376522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}