{"id":"W2149923399","doi":"10.1126/science.1201954","title":"A Crystal Structure of the Complex Between Human Complement Receptor 2 and Its Ligand C3d","year":2011,"lang":"en","type":"article","venue":"Science","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Complement (music); Crystal structure; Ligand (biochemistry); Chemistry; Crystallography; Receptor; Computational biology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002485861,0.0004075646,0.0005846162,0.0002044601,0.0006134874,0.0007379558,0.0008144287,0.0006766146,0.002274672],"category_scores_gemma":[0.0006100432,0.000261263,0.0002828206,0.0004681709,0.0002465169,0.0003217376,0.000268984,0.001266042,0.0003497271],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001541701,"about_ca_system_score_gemma":0.001508572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0134686,"about_ca_topic_score_gemma":0.01728502,"domain_scores_codex":[0.9998268,0.00001673158,0.000007865812,0.00003210306,0.0000874949,0.00002895431],"domain_scores_gemma":[0.9998354,0.00004187496,0.00002066896,0.00000808097,0.00005001081,0.00004400922],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002572555,0.0006871648,0.009355808,0.00205914,0.0005834846,0.005039036,0.0008735334,0.01344031,0.8279426,0.01096426,0.07691482,0.04956721],"study_design_scores_gemma":[0.002482265,0.001363269,0.08795661,0.0003252763,0.0009258548,0.007500265,0.001271205,0.1283857,0.4388686,0.004531319,0.3259576,0.000432014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9335335,0.02051798,0.01065755,0.004513226,0.001097313,0.0001577482,0.01267251,0.000686561,0.0161636],"genre_scores_gemma":[0.928335,0.008160574,0.02431325,0.0009028678,0.00009987714,0.0001185541,0.02639254,0.0001146466,0.0115627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0134686,"threshold_uncertainty_score":0.02678037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06515967091896947,"score_gpt":0.2940062839566217,"score_spread":0.2288466130376522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}