{"id":"W2149933439","doi":"10.1099/vir.0.81174-0","title":"Signal peptide peptidase promotes the formation of hepatitis C virus non-enveloped particles and is captured on the viral membrane during assembly","year":2005,"lang":"en","type":"article","venue":"Journal of General Virology","topic":"Hepatitis C virus research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Biology; Signal peptidase; Infectivity; Viral envelope; Cleavage (geology); Virus; Signal peptide; Cell biology; Virology; Yeast; Peptide; Biophysics; Biochemistry; Peptide sequence","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008065599,0.0001503351,0.0003655237,0.0001511444,0.0001641212,0.0000284809,0.000179225,0.0001042962,0.0002121633],"category_scores_gemma":[0.0002012744,0.00008098585,0.0001225061,0.0001248624,0.0002066161,0.0002258916,0.00006302315,0.0004954911,0.00001702166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007561812,"about_ca_system_score_gemma":0.0001075203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002479013,"about_ca_topic_score_gemma":0.0003730693,"domain_scores_codex":[0.9981641,0.0002826623,0.0006162231,0.0001268605,0.0004997483,0.000310442],"domain_scores_gemma":[0.9988944,0.0001877029,0.0003662326,0.0002000796,0.000217977,0.0001335892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007495765,0.000126753,0.007658998,0.00004311891,0.000112127,0.00007492516,0.001722708,0.0001914697,0.9832947,0.00005935198,0.001535894,0.004430352],"study_design_scores_gemma":[0.002003546,0.001482768,0.1297574,0.00007291012,0.00009046785,0.0004619842,0.00006834981,0.01956862,0.8451188,0.00008403647,0.001189241,0.0001018663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9827809,0.0001834459,0.0001580584,0.01622389,0.00004046758,0.0003032396,0.00001130223,0.000004992658,0.0002936634],"genre_scores_gemma":[0.9963364,0.0006728372,0.0006205818,0.001625136,0.0004535013,0.00001044882,0.000001948256,0.0000178451,0.0002612897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1381759,"threshold_uncertainty_score":0.3302507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02296966045748505,"score_gpt":0.283880238357143,"score_spread":0.2609105778996579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}