{"id":"W2149955599","doi":"10.1016/j.ijrobp.2003.08.024","title":"Phase III randomized study of radiotherapy plus procarbazine, lomustine, and vincristine with or without BUdR for treatment of anaplastic astrocytoma: final report of RTOG 9404","year":2004,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Centers for Disease Control and Prevention","keywords":"Lomustine; Medicine; Procarbazine; Vincristine; Temozolomide; Anaplastic astrocytoma; Oncology; Glioma; Internal medicine; Radiation therapy; External beam radiotherapy; Randomized controlled trial; Chemotherapy; Astrocytoma; Surgery; Brachytherapy; Cyclophosphamide; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002049948,0.002279618,0.004011991,0.0006245039,0.0007306973,0.001459952,0.002209394,0.001899631,0.007875883],"category_scores_gemma":[0.001615337,0.001244513,0.002191757,0.0007276984,0.0017012,0.001070359,0.0004902282,0.004971542,0.001938104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001576921,"about_ca_system_score_gemma":0.00220368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004042362,"about_ca_topic_score_gemma":0.009231037,"domain_scores_codex":[0.9992888,0.000422516,0.00002613785,0.0001054874,0.0000397549,0.0001172519],"domain_scores_gemma":[0.9987274,0.0003235759,0.000249476,0.0001281897,0.00005969442,0.0005117852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9653609,0.01257707,0.0006132079,0.0003121124,0.001340744,0.00004564113,0.0000833688,0.0007585963,0.003833127,0.0001529257,0.001694286,0.01322799],"study_design_scores_gemma":[0.93378,0.06283719,0.001413235,0.00001383713,0.0004821015,0.00004341005,0.00003112238,0.000306669,0.0003659229,0.0001219796,0.0005898721,0.00001471815],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867051,0.002997911,0.0008596227,0.001045915,0.0006621628,0.003090547,0.001912664,0.0002333092,0.002492826],"genre_scores_gemma":[0.9782528,0.003076464,0.00274466,0.001612256,0.0004730153,0.004784558,0.002517252,0.0001102968,0.006428748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007875883,"threshold_uncertainty_score":0.02634746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02950908672027092,"score_gpt":0.3688754236248729,"score_spread":0.3393663369046019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}