{"id":"W2149955599","doi":"10.1016/j.ijrobp.2003.08.024","title":"Phase III randomized study of radiotherapy plus procarbazine, lomustine, and vincristine with or without BUdR for treatment of anaplastic astrocytoma: final report of RTOG 9404","year":2004,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Centers for Disease Control and Prevention","keywords":"Lomustine; Medicine; Procarbazine; Vincristine; Temozolomide; Anaplastic astrocytoma; Oncology; Glioma; Internal medicine; Radiation therapy; External beam radiotherapy; Randomized controlled trial; Chemotherapy; Astrocytoma; Surgery; Brachytherapy; Cyclophosphamide; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003736262,0.0002423928,0.001698357,0.0002383694,0.00003466189,0.000006195233,0.0001131172,0.0001017569,0.00001176743],"category_scores_gemma":[0.0002945883,0.0001497365,0.0002243539,0.0001522168,0.0002694168,0.00009035439,0.00001369332,0.00008403108,1.588579e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005403255,"about_ca_system_score_gemma":0.0008947287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001001008,"about_ca_topic_score_gemma":0.00005473653,"domain_scores_codex":[0.9978675,0.0001062892,0.001349591,0.0002308843,0.0002951803,0.0001505806],"domain_scores_gemma":[0.9953627,0.0006546754,0.002600048,0.0001488175,0.001134585,0.00009919782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7348901,0.03379719,0.1577174,0.0001077335,0.01087536,0.0008399657,0.003277946,0.004643289,0.00871028,0.001355701,0.00006662263,0.04371837],"study_design_scores_gemma":[0.8782533,0.09627238,0.004846092,0.0001976789,0.001940481,0.002081104,0.000339963,0.002631103,0.01269407,0.0003303726,0.0002672523,0.0001462056],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804491,0.0005148301,0.01669786,0.0003969936,0.0002629725,0.001585259,0.00006141228,0.000009627776,0.00002190667],"genre_scores_gemma":[0.9865067,0.000341371,0.01249943,0.00003156633,0.0004033549,0.0001076595,0.00006909931,0.00002337229,0.0000174294],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1528713,"threshold_uncertainty_score":0.6106079,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02950908672027092,"score_gpt":0.3688754236248729,"score_spread":0.3393663369046019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}