{"id":"W2149957846","doi":"10.1016/j.ejca.2008.03.005","title":"A comparison of CDKN2A mutation detection within the Melanoma Genetics Consortium (GenoMEL)","year":2008,"lang":"en","type":"article","venue":"European Journal of Cancer","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Medical Research Council; National Health and Medical Research Council; National Cancer Institute; Cancer Research UK; National Institutes of Health; Australian Cancer Research Foundation; Associazione Italiana per la Ricerca sul Cancro; Foundation for the National Institutes of Health","keywords":"CDKN2A; Genetics; Mutation; Biology; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007108457,0.0004052026,0.0005873347,0.005359444,0.0009123177,0.001934211,0.001033362,0.001186472,0.002605543],"category_scores_gemma":[0.01581569,0.0002851254,0.0004922497,0.002927411,0.0005176646,0.0006544162,0.002018139,0.0005123243,0.0008656523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002656519,"about_ca_system_score_gemma":0.001822368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04450218,"about_ca_topic_score_gemma":0.05728273,"domain_scores_codex":[0.9936248,0.001894529,0.0003671419,0.00149715,0.001632366,0.0009839108],"domain_scores_gemma":[0.9876946,0.003552741,0.001365329,0.00102631,0.004673269,0.001687696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001821072,0.0001145903,0.943365,0.0001203277,0.0003263954,0.0004362486,0.0009033956,0.000669374,0.01174252,0.000713922,0.006551117,0.03323605],"study_design_scores_gemma":[0.0000727909,0.0001701968,0.9850978,0.00004212983,0.0001335983,0.0008244264,0.0006738167,0.00122228,0.005026463,0.0001864995,0.006520907,0.00002916963],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789367,0.001161056,0.001303572,0.0009639694,0.0000452778,0.00006651662,0.01135173,0.0002078378,0.005963254],"genre_scores_gemma":[0.9837486,0.0002026985,0.002163497,0.0004148863,0.0000244907,0.00007216693,0.01212034,0.0001136489,0.001139604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04450218,"threshold_uncertainty_score":0.08848625,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02095708164308003,"score_gpt":0.2814506169532459,"score_spread":0.2604935353101659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}