{"id":"W2149983483","doi":"10.3747/co.20.1497","title":"Denosumab and Giant Cell Tumour of Bone—A Review and Future Management Considerations","year":2013,"lang":"en","type":"review","venue":"Current Oncology","topic":"Bone Tumor Diagnosis and Treatments","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Denosumab; Medicine; Giant cell; RANKL; Osteoclast; Giant-cell tumor of bone; Cancer research; Pathology; Activator (genetics); Receptor; Internal medicine; Osteoporosis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004194701,0.0006891044,0.001314151,0.002580577,0.0003424723,0.0008877647,0.0008078418,0.001196512,0.003567232],"category_scores_gemma":[0.0006946831,0.000283934,0.0005316764,0.002571341,0.0003984347,0.001611948,0.0004665126,0.00159618,0.001500344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006658752,"about_ca_system_score_gemma":0.001113305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001395474,"about_ca_topic_score_gemma":0.003244407,"domain_scores_codex":[0.9998384,0.0000263015,0.0000371859,0.00002688539,0.00005801804,0.00001324778],"domain_scores_gemma":[0.9996936,0.0001358017,0.00005719373,0.000006786462,0.00007895739,0.00002758322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008605667,0.00009601963,0.000293343,0.02067181,0.00009711609,0.0009119885,0.00008828862,0.0003436949,0.0009019019,0.002446783,0.05161561,0.9224473],"study_design_scores_gemma":[0.00002924074,0.0001025638,0.001204854,0.008122367,0.0001710442,0.006679161,0.0001555164,0.0001281275,0.0001991672,0.002139217,0.9810433,0.00002538353],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007376667,0.998804,0.00003880193,0.0004015629,0.0002160243,0.000002488568,0.000007795813,0.000002933047,0.0004526461],"genre_scores_gemma":[0.0003850193,0.9985971,0.0001033873,0.0003064075,0.0003102566,0.000003720928,0.00001640761,6.927066e-7,0.0002769717],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003567232,"threshold_uncertainty_score":0.01193357,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1192975730936035,"score_gpt":0.4197027516051755,"score_spread":0.3004051785115721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}