{"id":"W2149990806","doi":"10.1128/iai.72.8.4486-4493.2004","title":"Characterization of an I-E-Restricted, gp63-Specific, CD4-T-Cell Clone from<i>Leishmania major</i>-Resistant C3H Mice That Secretes Type 2 Cytokines and Exacerbates Infection with<i>L. major</i>","year":2004,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Biology; Epitope; clone (Java method); Leishmania major; Immune system; Immunology; Context (archaeology); Proinflammatory cytokine; Leishmania; T cell; Cutaneous leishmaniasis; Virology; Molecular biology; Antigen; Inflammation; Parasite hosting; Leishmaniasis; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001187343,0.0003599713,0.0002714782,0.0002449254,0.0001649298,0.0003531415,0.0001992781,0.000394353,0.001135163],"category_scores_gemma":[0.0002209406,0.0001559502,0.0002409944,0.0001437943,0.0001760863,0.000148385,0.0001413426,0.0009015228,0.00079476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002161571,"about_ca_system_score_gemma":0.0001804081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006648705,"about_ca_topic_score_gemma":0.0007260463,"domain_scores_codex":[0.9998686,0.00001489032,0.00001279107,0.00002552804,0.00003536715,0.00004277439],"domain_scores_gemma":[0.9997514,0.00005843232,0.00004695755,0.00004106149,0.00004114773,0.00006103074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007153206,0.00004028359,0.0001754344,0.00001265991,0.000002023197,0.00005038466,0.000009862855,0.00002017485,0.9991103,0.00001867432,0.00002001569,0.0004686145],"study_design_scores_gemma":[0.000319666,0.001967299,0.02549297,0.0000166589,0.00006398694,0.002687918,0.0000629536,0.001168953,0.9638182,0.00008004747,0.004308221,0.00001319432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951662,0.0005627533,0.001903227,0.0001166749,0.00002607626,0.00009534779,0.0006349094,0.00005251758,0.001442175],"genre_scores_gemma":[0.9909409,0.000441903,0.003239434,0.0001501289,0.00003726916,0.0001094225,0.002756226,0.00003646295,0.002288324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001135163,"threshold_uncertainty_score":0.003797531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01987890565911341,"score_gpt":0.2507334980563327,"score_spread":0.2308545923972193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}