{"id":"W2150003781","doi":"10.1002/pbc.24398","title":"Phase I/II trial of clofarabine and cytarabine in children with relapsed/refractory acute lymphoblastic leukemia (AAML0523): A report from the Children's Oncology Group","year":2013,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Sanofi Genzyme; National Institutes of Health","keywords":"Clofarabine; Medicine; Cytarabine; Refractory (planetary science); Internal medicine; Oncology; Chemotherapy; Stage (stratigraphy); Nucleoside analogue; Leukemia; Phases of clinical research; Gastroenterology; Nucleoside","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002157906,0.001179136,0.001668373,0.0004275033,0.0003905285,0.0008166524,0.0009755734,0.001102323,0.001336305],"category_scores_gemma":[0.0009907306,0.0003483772,0.001079873,0.000597339,0.0007681414,0.0004174483,0.0003608784,0.002699395,0.0003776903],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001204666,"about_ca_system_score_gemma":0.002176821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002675108,"about_ca_topic_score_gemma":0.005658054,"domain_scores_codex":[0.999274,0.0004167272,0.00005398842,0.00008971847,0.0000798283,0.0000858758],"domain_scores_gemma":[0.9990466,0.0001901492,0.0001695425,0.00006567533,0.00004307636,0.0004848592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5317257,0.06607783,0.04431644,0.001410316,0.004257121,0.002429839,0.001256254,0.005151327,0.06750798,0.0007249272,0.01209741,0.2630449],"study_design_scores_gemma":[0.468124,0.4600548,0.0441429,0.0001287419,0.001187025,0.002588223,0.000157902,0.001419688,0.01053024,0.0001866247,0.01143333,0.00004662242],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895159,0.005921536,0.0003076798,0.0005884266,0.00005996727,0.001668651,0.0008825246,0.00008263236,0.0009726542],"genre_scores_gemma":[0.9869082,0.003139282,0.003139708,0.001052386,0.0001512313,0.002051017,0.002542617,0.00003005987,0.0009855841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002675108,"threshold_uncertainty_score":0.01141226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00827143318028918,"score_gpt":0.2750124902387742,"score_spread":0.2667410570584851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}