{"id":"W2150003781","doi":"10.1002/pbc.24398","title":"Phase I/II trial of clofarabine and cytarabine in children with relapsed/refractory acute lymphoblastic leukemia (AAML0523): A report from the Children's Oncology Group","year":2013,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; Sanofi Genzyme; National Institutes of Health","keywords":"Clofarabine; Medicine; Cytarabine; Refractory (planetary science); Internal medicine; Oncology; Chemotherapy; Stage (stratigraphy); Nucleoside analogue; Leukemia; Phases of clinical research; Gastroenterology; Nucleoside","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005258055,0.0004976909,0.001120122,0.000325223,0.0001549819,0.00003127957,0.0003946572,0.0003888853,0.0004463521],"category_scores_gemma":[0.0004051463,0.0003196982,0.000145474,0.0009755761,0.0004389179,0.000245617,0.0003065001,0.00085246,0.00002005123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001043669,"about_ca_system_score_gemma":0.003713182,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01873396,"about_ca_topic_score_gemma":0.0003250559,"domain_scores_codex":[0.9960389,0.0001905354,0.001092637,0.0009429343,0.0009532149,0.0007818251],"domain_scores_gemma":[0.9971063,0.0006860654,0.0006540909,0.0009127797,0.0002498812,0.0003909524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05581052,0.009673712,0.8835217,0.0001289998,0.00384376,0.0009304681,0.001042689,0.00004377317,0.003457016,0.00002415872,0.016009,0.02551416],"study_design_scores_gemma":[0.4391374,0.01892713,0.5323002,0.0001423449,0.005439195,0.00202621,0.00005549089,0.0003682404,0.0003719122,0.00007580794,0.0005677304,0.0005883375],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917304,0.00332783,0.00005299324,0.00102735,0.0002373168,0.003183366,0.0001874559,0.00006852346,0.0001847567],"genre_scores_gemma":[0.9898517,0.005089568,0.0006316138,0.000430506,0.002585057,0.0007666395,0.0002673245,0.00009580166,0.0002817954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3833269,"threshold_uncertainty_score":0.9999255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00827143318028918,"score_gpt":0.2750124902387742,"score_spread":0.2667410570584851,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}