{"id":"W2150012432","doi":"10.1093/infdis/jir506","title":"Optimizing Initial Therapy for HIV Infection","year":2011,"lang":"en","type":"letter","venue":"The Journal of Infectious Diseases","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Atazanavir; Efavirenz; Abacavir; Emtricitabine; Hazard ratio; Lamivudine; Viral load; Lopinavir; Raltegravir; Medicine; Confidence interval; Internal medicine; Virology; Human immunodeficiency virus (HIV); Antiretroviral therapy; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003777636,0.0004085298,0.0004752587,0.000271999,0.0008704724,0.0007386418,0.0004168067,0.001694626,0.009551538],"category_scores_gemma":[0.002657627,0.00008790914,0.0002963179,0.0001454624,0.0002901846,0.0008495402,0.0005587211,0.003071387,0.004426403],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001063549,"about_ca_system_score_gemma":0.0009435595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007937733,"about_ca_topic_score_gemma":0.002540755,"domain_scores_codex":[0.9997081,0.00009215732,0.00002728783,0.00003086457,0.00009003135,0.00005158644],"domain_scores_gemma":[0.9995952,0.000119088,0.0000457227,0.0000240115,0.0000809421,0.0001350749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003142078,0.0006239896,0.01052427,0.0006710411,0.00003136017,0.01463949,0.0004596767,0.0005001647,0.003672491,0.00896858,0.4891634,0.4704313],"study_design_scores_gemma":[0.0001075456,0.0006179425,0.01260481,0.00285434,0.00004244172,0.03294301,0.0003094152,0.0007701942,0.001554638,0.01451244,0.9336446,0.00003857944],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03689525,0.1832423,0.01629108,0.3823171,0.0188903,0.0007449516,0.0003838901,0.0007982741,0.3604368],"genre_scores_gemma":[0.2986118,0.1698112,0.03193892,0.2929493,0.07083858,0.0006200242,0.0005962646,0.0002615365,0.1343723],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.009551538,"threshold_uncertainty_score":0.03195304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02517830726059587,"score_gpt":0.2846655624079437,"score_spread":0.2594872551473478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}