{"id":"W2150014596","doi":"10.4049/jimmunol.174.12.7986","title":"Mechanisms of Mucosal and Parenteral Tuberculosis Vaccinations: Adenoviral-Based Mucosal Immunization Preferentially Elicits Sustained Accumulation of Immune Protective CD4 and CD8 T Cells within the Airway Lumen","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":165,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Colorado State University","keywords":"Immune system; Immunology; Tuberculosis vaccines; Spleen; Immunization; CD8; Vaccination; CTL*; Medicine; T cell; Population; Mycobacterium tuberculosis; Biology; Tuberculosis; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001569935,0.0002679768,0.0005645301,0.0003418374,0.0003411851,0.00001692728,0.0004958069,0.0002824288,0.000107122],"category_scores_gemma":[0.0002650502,0.0001673264,0.0001415485,0.0002610725,0.0003968939,0.0003221648,0.0001540137,0.0005942738,0.000003657886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006794477,"about_ca_system_score_gemma":0.0002068754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001586667,"about_ca_topic_score_gemma":0.00002708677,"domain_scores_codex":[0.9964719,0.001767178,0.001221351,0.0001516577,0.0001073381,0.0002806125],"domain_scores_gemma":[0.9967244,0.0006851532,0.001602632,0.0003822666,0.0005924967,0.00001310598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005636234,0.0002405753,0.0001138869,0.00003635231,0.0009310046,4.413887e-7,0.00368583,0.0004759705,0.9818199,0.001220112,0.00002095779,0.005818747],"study_design_scores_gemma":[0.004796315,0.002129348,0.02749798,0.0001364293,0.0003304017,0.000167825,0.002824383,0.000255513,0.9605677,0.001002108,0.0001105003,0.0001814654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.974338,0.016226,0.006942057,0.001441536,0.0003289999,0.0006724648,0.00001768552,0.00001527129,0.00001801122],"genre_scores_gemma":[0.9981597,0.00124299,0.0003141542,0.00006701938,0.00001839237,0.00001443287,0.00002057327,0.00002725088,0.0001354575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02738409,"threshold_uncertainty_score":0.6823374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01279933480262201,"score_gpt":0.2530242188560505,"score_spread":0.2402248840534285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}