{"id":"W2150095362","doi":"10.1158/1078-0432.ccr-07-4430","title":"Monoclonal Antibody CC188 Binds a Carbohydrate Epitope Expressed on the Surface of Both Colorectal Cancer Stem Cells and their Differentiated Progeny","year":2008,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute; National Institute of Biomedical Imaging and Bioengineering; China Scholarship Council","keywords":"Epitope; Monoclonal antibody; Cancer stem cell; Cancer research; Biology; Molecular biology; Colorectal cancer; CD44; Cancer cell; Antibody; Stem cell; Cancer; Pathology; Immunology; Cell; Medicine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001655469,0.0002630863,0.0008057316,0.0001081701,0.0002624678,0.00002868321,0.0003090691,0.0001941595,0.0004413754],"category_scores_gemma":[0.00009522391,0.0001520219,0.0002478292,0.0006371393,0.001428152,0.00004599106,0.0002213673,0.001078873,0.00001069764],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001349586,"about_ca_system_score_gemma":0.001100784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002627414,"about_ca_topic_score_gemma":0.0002620907,"domain_scores_codex":[0.996447,0.0007205454,0.00069539,0.0006678458,0.0008127578,0.0006564381],"domain_scores_gemma":[0.9971419,0.001305073,0.0001790434,0.0005274193,0.0004610905,0.0003854997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00493127,0.001006209,0.105101,0.0002730591,0.0006107484,0.00007162357,0.000912285,0.00005056933,0.8686686,0.00007679652,0.004662528,0.01363532],"study_design_scores_gemma":[0.004515888,0.002025113,0.1025553,0.0005623249,0.0001219014,0.000008524987,0.0003286517,0.0009957526,0.8799128,0.00005482548,0.008600089,0.0003188033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912134,0.004569969,0.00000807035,0.001941691,0.000362929,0.001243877,0.000364635,0.00002899845,0.0002664406],"genre_scores_gemma":[0.9777099,0.0206304,0.00002204209,0.0001883231,0.0003454518,0.000183199,0.00001179795,0.0000506365,0.0008581844],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01606043,"threshold_uncertainty_score":0.6199273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2128003088883914,"score_gpt":0.4499773466016272,"score_spread":0.2371770377132358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}