{"id":"W2150095362","doi":"10.1158/1078-0432.ccr-07-4430","title":"Monoclonal Antibody CC188 Binds a Carbohydrate Epitope Expressed on the Surface of Both Colorectal Cancer Stem Cells and their Differentiated Progeny","year":2008,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute; National Institute of Biomedical Imaging and Bioengineering; China Scholarship Council","keywords":"Epitope; Monoclonal antibody; Cancer stem cell; Cancer research; Biology; Molecular biology; Colorectal cancer; CD44; Cancer cell; Antibody; Stem cell; Cancer; Pathology; Immunology; Cell; Medicine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001269272,0.000455335,0.0002262779,0.0003041736,0.0001222493,0.0001619925,0.0001932439,0.0002599657,0.002438584],"category_scores_gemma":[0.0001556835,0.0001104856,0.0002914812,0.0001691404,0.000159738,0.0001609813,0.0001504262,0.0003767401,0.0006368091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003929137,"about_ca_system_score_gemma":0.0002089393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008128684,"about_ca_topic_score_gemma":0.001111861,"domain_scores_codex":[0.9998251,0.00003239558,0.00001197967,0.00004053102,0.00004469098,0.00004536091],"domain_scores_gemma":[0.9999006,0.00002218658,0.0000254207,0.00001196447,0.0000204064,0.00001944062],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009129049,0.00002387303,0.001073774,0.00006104791,0.000007818948,0.00008838538,0.00001153065,0.0000676268,0.9947222,0.00009127804,0.000117524,0.003643485],"study_design_scores_gemma":[0.00004853784,0.0006070422,0.01270526,0.00002452362,0.0000768231,0.001596426,0.00004434746,0.001074986,0.9713205,0.00003479445,0.01245999,0.000006976073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837923,0.003599218,0.008448455,0.0001770156,0.00004085819,0.00009119473,0.000252504,0.00009141189,0.003507143],"genre_scores_gemma":[0.9880944,0.001883056,0.00662176,0.0000883558,0.00003032056,0.00007250649,0.0006263386,0.00001849738,0.00256482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002438584,"threshold_uncertainty_score":0.008157849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2128003088883914,"score_gpt":0.4499773466016272,"score_spread":0.2371770377132358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}