{"id":"W2150165177","doi":"10.1189/jlb.0909633","title":"Optimal TLR9 signal converts tolerogenic CD4–8– DCs into immunogenic ones capable of stimulating antitumor immunity via activating CD4+ Th1/Th17 and NK cell responses","year":2010,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Biology; TLR9; Immunity; Immunology; Cell biology; Immune system; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009505801,0.0001945449,0.0001373408,0.00009035326,0.00006676502,0.0002372809,0.0001035585,0.0001813918,0.00252999],"category_scores_gemma":[0.0001083598,0.00009047646,0.0001142947,0.00005020923,0.0001363888,0.0001252357,0.0001270403,0.0004742434,0.0005576233],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001723364,"about_ca_system_score_gemma":0.0001387417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009552781,"about_ca_topic_score_gemma":0.0001476332,"domain_scores_codex":[0.9998695,0.00002985045,0.00001456047,0.0000177636,0.00002282767,0.00004545534],"domain_scores_gemma":[0.9999138,0.00001794166,0.000027225,0.000007632473,0.000009440813,0.0000240156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001086405,0.00003401098,0.0001160926,0.00001608331,0.000001729509,0.00002068583,0.000002460952,0.00005910918,0.9991571,0.00004885787,0.00002397748,0.0004111694],"study_design_scores_gemma":[0.00001860959,0.0002586704,0.000798535,0.000004117014,0.000005629062,0.00009473215,0.00001657861,0.0005363306,0.9971209,0.00004335897,0.001100903,0.000001562402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969788,0.0003199979,0.001412203,0.00005993849,0.00003049618,0.00001432862,0.0001825539,0.00003479623,0.0009669256],"genre_scores_gemma":[0.9959359,0.0001508278,0.001910608,0.00003663465,0.00001192508,0.00002134249,0.0004279593,0.0000101705,0.001494758],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00252999,"threshold_uncertainty_score":0.008463621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01221397017478894,"score_gpt":0.2564168013338534,"score_spread":0.2442028311590644,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}