{"id":"W2150236759","doi":"10.1152/ajpcell.00323.2014","title":"Atrial natriuretic peptide inhibits cell cycle activity of embryonic cardiac progenitor cells via its NPRA receptor signaling axis","year":2015,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Victor Chang Cardiac Research Institute","keywords":"Atrial natriuretic peptide; Internal medicine; Paracrine signalling; NPR1; Endocrinology; NPR2; Receptor; Natriuretic peptide; Signal transduction; Cell biology; Embryonic stem cell; Autocrine signalling; Chemistry; Biology; Medicine; Heart failure; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009330407,0.0002256961,0.0002484235,0.0001594221,0.0001225725,0.0001786877,0.0001525081,0.00013666,0.0008649841],"category_scores_gemma":[0.00007140812,0.0000893191,0.0001510134,0.00009794965,0.0001261336,0.0001403738,0.0001526468,0.0006025508,0.0002207732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001351422,"about_ca_system_score_gemma":0.0002806139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005110328,"about_ca_topic_score_gemma":0.001147409,"domain_scores_codex":[0.9998863,0.00001740779,0.00001526155,0.0000239262,0.00003291381,0.00002421848],"domain_scores_gemma":[0.999946,0.00001108245,0.00001039404,0.000005589587,0.000006997867,0.00001997197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001338889,0.00005625044,0.0001429904,0.00004528622,0.000004017602,0.00005515336,0.00001980562,0.00004331474,0.996576,0.0001016706,0.00006726867,0.002754242],"study_design_scores_gemma":[0.00004116006,0.0008563642,0.009148086,0.00001074757,0.00001778057,0.0002010276,0.00004417119,0.001205447,0.9836363,0.00008855414,0.00474591,0.00000433062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902063,0.004040858,0.002057401,0.0001349407,0.00005252469,0.00003501616,0.0003454376,0.00006611953,0.003061359],"genre_scores_gemma":[0.9897424,0.002838068,0.00255519,0.0001237815,0.00002419872,0.00009614406,0.0006368309,0.00001765806,0.003965793],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008649841,"threshold_uncertainty_score":0.002893627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054675456466829,"score_gpt":0.2613695879054985,"score_spread":0.2508228333408302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}