{"id":"W2150240056","doi":"10.1172/jci40115","title":"Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys","year":2009,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":401,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; Yerkes National Primate Research Center, Emory University; National Institutes of Health; Canadian Institutes of Health Research; Li Ka Shing Foundation; Center for AIDS Research, University of Washington; Emory University; University of Pennsylvania","keywords":"Innate immune system; Immune system; Biology; Immunology; Simian immunodeficiency virus; Immunity; Downregulation and upregulation; Phenotype; Virology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00380223,0.0001317679,0.0009824532,0.0004244802,0.00003141425,0.00001378846,0.00007407391,0.0002079248,0.00006546082],"category_scores_gemma":[0.003667062,0.0001029567,0.000513897,0.00118221,0.0001195671,0.0001415967,0.000008340859,0.0003306766,0.000007697597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001884975,"about_ca_system_score_gemma":0.0003834639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000388152,"about_ca_topic_score_gemma":0.00002488961,"domain_scores_codex":[0.9963176,0.0009157559,0.002151488,0.0001612841,0.0002935545,0.0001603415],"domain_scores_gemma":[0.9971763,0.0006018305,0.001300027,0.0002164623,0.0004331579,0.0002721644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.004460801,0.0007444592,0.9735572,0.00001216434,0.00106927,0.0001127159,0.00004877428,0.003082476,0.001991028,0.00008510923,0.0001816526,0.01465435],"study_design_scores_gemma":[0.006309541,0.002115163,0.9856964,0.0001303261,0.001443645,0.00003877021,0.00001158173,0.002164397,0.0001796485,0.001628146,0.0002095069,0.00007290341],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995286,0.0001705167,0.001896489,0.002084909,0.0001272017,0.0002146409,0.00001396879,0.00001081534,0.0001954683],"genre_scores_gemma":[0.9964563,0.0001015126,0.002267431,0.0009824433,0.00014593,0.000001662963,0.000008038074,0.00000588903,0.00003074976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01458145,"threshold_uncertainty_score":0.4390081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05874832140545877,"score_gpt":0.3811057037450673,"score_spread":0.3223573823396085,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}