{"id":"W2150265306","doi":"10.1093/glycob/cwu009","title":"Structural basis for selective cross-reactivity in a bactericidal antibody against inner core lipooligosaccharide from Neisseria meningitidis†,‡","year":2014,"lang":"en","type":"article","venue":"Glycobiology","topic":"Bacterial Infections and Vaccines","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of Victoria","funders":"National Research Council Canada; Western Economic Diversification Canada; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC; Canadian Light Source","keywords":"Neisseria meningitidis; Epitope; Chemistry; Inner core; Antibody; Monoclonal antibody; Glycan; Antigen; Serine; Bacterial outer membrane; Microbiology; Biology; Glycoprotein; Biochemistry; Genetics; Escherichia coli; Bacteria; Gene; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002370323,0.0003252022,0.0006161864,0.0001701252,0.0002563101,0.00003837992,0.000225376,0.000576406,0.0003326838],"category_scores_gemma":[0.0003793372,0.000280832,0.000144273,0.0002077966,0.0001784645,0.0001960071,0.0001087531,0.0003519345,0.00009640741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008241559,"about_ca_system_score_gemma":0.00006241843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002108621,"about_ca_topic_score_gemma":0.0009130153,"domain_scores_codex":[0.9980989,0.0002369725,0.0004355084,0.0006041608,0.00000919776,0.0006152569],"domain_scores_gemma":[0.9987282,0.0005877868,0.0002135024,0.000305278,0.0001318372,0.00003336707],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007730281,0.00005892938,0.135604,0.000006914001,0.0001155096,5.088963e-7,0.000169023,0.000008634558,0.8593303,0.0003938897,0.0002433086,0.003295935],"study_design_scores_gemma":[0.003178339,0.0005928194,0.7749265,0.00002773848,0.00004550638,0.00005115205,0.00005707165,0.00009521879,0.1995517,0.001083779,0.01990216,0.0004880216],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952789,0.0001080414,0.0001818493,0.00009592075,0.003054,0.0003962887,0.0005038797,0.0001007313,0.0002804187],"genre_scores_gemma":[0.9973098,0.00001599244,0.0001381961,0.0001387339,0.0003219452,0.0001020456,0.001824686,0.00002917787,0.0001194192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6597786,"threshold_uncertainty_score":0.9999644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01672264866105489,"score_gpt":0.2890500767042148,"score_spread":0.2723274280431599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}