{"id":"W2150300764","doi":"10.1073/pnas.1101459108","title":"Electronic properties of the highly ruffled heme bound to the heme degrading enzyme IsdI","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Heme Oxygenase-1 and Carbon Monoxide","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Biological and Environmental Research; National Center for Research Resources; National Institute of General Medical Sciences; Uehara Memorial Foundation; Canadian Institutes of Health Research; National Institutes of Health; Basic Energy Sciences; Biotechnology and Biological Sciences Research Council; Canadian Blood Services; U.S. Department of Energy","keywords":"Heme; Biliverdin; Chemistry; Heme oxygenase; Hemeprotein; Enzyme; Biochemistry; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001045665,0.0001105243,0.0001407498,0.000226153,0.0001831864,0.0002119183,0.0003130083,0.0002244949,0.001538298],"category_scores_gemma":[0.0002836977,0.00007436969,0.0000610564,0.0003001722,0.0002981417,0.0001129196,0.0001272845,0.0003251533,0.0001892987],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001745374,"about_ca_system_score_gemma":0.00006743142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006516112,"about_ca_topic_score_gemma":0.000303723,"domain_scores_codex":[0.9999182,0.000008765696,0.00000231485,0.00001499277,0.00003763633,0.00001813406],"domain_scores_gemma":[0.9998304,0.00006039096,0.00003575396,0.00001197534,0.00003640438,0.00002511424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001540053,0.000034218,0.001178936,0.00004704706,0.00001327828,0.0001765649,0.00009341162,0.0002886476,0.995263,0.0004885735,0.0001598079,0.002102468],"study_design_scores_gemma":[0.00004264129,0.0005725059,0.03814992,0.00001965498,0.00003031076,0.0009449793,0.0004641414,0.01090574,0.9441188,0.0006932162,0.004019919,0.00003814911],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997833,0.0002885142,0.0007747136,0.00004994384,0.000009432288,0.000001508357,0.00004807855,0.00001271285,0.0009821244],"genre_scores_gemma":[0.9986935,0.0001104391,0.0002604928,0.0000209539,0.000004591392,0.0000016343,0.0001512336,0.000005750136,0.000751381],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001538298,"threshold_uncertainty_score":0.005146146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03957037864957915,"score_gpt":0.2578098193659627,"score_spread":0.2182394407163835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}