{"id":"W2150351516","doi":"10.1038/sj.emboj.7600193","title":"Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases","year":2004,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":461,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Biology; Phosphorylation; Kinase; Translation (biology); Protein-Serine-Threonine Kinases; Cell biology; Eukaryotic translation; Biochemistry; Protein kinase A; Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001758171,0.0001100815,0.0001035628,0.00003247999,0.0001108748,0.00002530546,0.000150842,0.00009115866,0.0001023037],"category_scores_gemma":[0.00003028958,0.00008676663,0.0000886697,0.00009575531,0.0000470842,0.00001675964,0.00001209541,0.0001338749,0.000004490639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004501148,"about_ca_system_score_gemma":0.0001069466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001775802,"about_ca_topic_score_gemma":0.000003680056,"domain_scores_codex":[0.9991949,0.0000634154,0.0002653143,0.0001267442,0.0002077055,0.0001419074],"domain_scores_gemma":[0.9994314,0.00001408177,0.0002176692,0.0001592896,0.0001320314,0.00004558417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009851171,0.00004177413,0.0007189606,0.000008786677,0.00006833108,0.000001020211,0.0003642569,0.005282142,0.9891389,0.00001165548,0.0007653774,0.003500284],"study_design_scores_gemma":[0.000875398,0.00023715,0.004657978,0.00003937352,0.00004128546,0.00004248982,0.00004394554,0.0003092591,0.991701,0.001034506,0.0008914723,0.0001261576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889761,0.002244041,0.007738856,0.0005234924,0.0002285176,0.0001058221,0.00003973729,0.000007343112,0.0001360956],"genre_scores_gemma":[0.9989144,0.0002813011,0.0002209122,0.0002435965,0.0002155482,0.000002726695,0.00005867965,0.00001805472,0.00004474051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009938346,"threshold_uncertainty_score":0.353824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01953548530711837,"score_gpt":0.2634090508565731,"score_spread":0.2438735655494547,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}