{"id":"W2150372822","doi":"10.3109/03630269.2010.511591","title":"New and Known β-Thalassemia Determinants Masked by Known and New δ Gene Defects [Hb A<sub>2</sub>-Ramallah or δ6(A3)Glu→Gln,<i>G</i>AG&gt;&gt;<i>C</i>AG]","year":2010,"lang":"en","type":"article","venue":"Hemoglobin","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Waterloo","keywords":"Microcytic anemia; Frameshift mutation; Thalassemia; Gene; Genetics; Molecular biology; Stop codon; Compound heterozygosity; Biology; Globin; Phenotype; Chemistry; Hemoglobin; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003928643,0.0009359396,0.001216318,0.0002715318,0.0003646543,0.0002046775,0.0003274842,0.001135481,0.0003530828],"category_scores_gemma":[0.0003887573,0.0007554053,0.0002362708,0.0006707091,0.0003402985,0.0003069729,0.0003329525,0.001250257,0.0002748076],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001114236,"about_ca_system_score_gemma":0.0009075351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002904502,"about_ca_topic_score_gemma":0.0005807795,"domain_scores_codex":[0.9956561,0.0001005058,0.0008842186,0.001326222,0.0006470972,0.001385867],"domain_scores_gemma":[0.9963766,0.0002260638,0.0003077745,0.0009806775,0.0001485837,0.001960313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006243219,0.0002424996,0.01110822,0.0002937603,0.0001423797,0.0005246577,0.000473685,0.000001327087,0.7145669,0.00005907318,0.1157831,0.1561801],"study_design_scores_gemma":[0.02184438,0.002084629,0.02331862,0.00102342,0.001194221,0.005788991,0.0003227674,0.000821276,0.5391698,0.0006060474,0.4013341,0.002491663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985332,0.007717452,0.0001752666,0.001687238,0.001040484,0.001261643,0.00004950089,0.0003288354,0.002407656],"genre_scores_gemma":[0.9759001,0.005619365,0.003426285,0.001917655,0.0008073187,0.00004188434,0.00009765904,0.000247814,0.01194189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.285551,"threshold_uncertainty_score":0.9994897,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008291168292736741,"score_gpt":0.2338596403629186,"score_spread":0.2255684720701818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}