{"id":"W2150460695","doi":"10.1093/ndt/gfu069","title":"A pilot study to determine the dose and effectiveness of adrenocorticotrophic hormone (H.P. Acthar(R) Gel) in nephrotic syndrome due to idiopathic membranous nephropathy","year":2014,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Renal Diseases and Glomerulopathies","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Center for Advancing Translational Sciences","keywords":"Medicine; Nephrotic syndrome; Proteinuria; Internal medicine; Membranous nephropathy; Renal function; Endocrinology; Nephropathy; Glomerulonephritis; Gastroenterology; Urology; Kidney; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00109996,0.0003083558,0.000984185,0.000566027,0.0001065164,0.00002448564,0.000157445,0.00006629035,0.000009982227],"category_scores_gemma":[0.0001852532,0.0002283081,0.0001094914,0.0008646098,0.0001316112,0.000107166,0.00003664618,0.000229363,0.00002100768],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000433238,"about_ca_system_score_gemma":0.00006388812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007249982,"about_ca_topic_score_gemma":0.0008376405,"domain_scores_codex":[0.9969934,0.001080984,0.0006431548,0.0005436043,0.0003554207,0.0003834791],"domain_scores_gemma":[0.9984916,0.0005707954,0.0001326934,0.0004521648,0.0001131757,0.0002395552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.04444127,0.004463586,0.1367436,0.00226862,0.0006768957,0.002942752,0.009939566,0.002750388,0.786341,0.0001305686,0.000006088705,0.009295691],"study_design_scores_gemma":[0.004907924,0.01672579,0.9740669,0.0002522794,0.001461953,0.0007507975,0.0001251994,0.0003999934,0.0009866678,0.0001099645,0.000005890859,0.0002066586],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955568,0.0005133068,0.001074358,0.0003330585,0.00006657842,0.002374086,0.00001918565,0.00004204203,0.00002058049],"genre_scores_gemma":[0.9983885,0.0002074132,0.00008747828,0.0007792118,0.00005912526,0.0004117154,0.00002945898,0.00003387876,0.000003239412],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8373233,"threshold_uncertainty_score":0.9310132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119996497931524,"score_gpt":0.2470912079536774,"score_spread":0.2358912429743622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}