{"id":"W2150472661","doi":"10.1128/jvi.80.7.3189-3204.2006","title":"Acetylated Tat Regulates Human Immunodeficiency Virus Type 1 Splicing through Its Interaction with the Splicing Regulator p32","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; U.S. Public Health Service; National Institutes of Health; University of St Andrews; George Washington University","keywords":"Biology; Acetylation; RNA splicing; Transactivation; Molecular biology; Transcription (linguistics); Protein splicing; HIV Long Terminal Repeat; Histone; Immunoprecipitation; Cell biology; Transcription factor; Biochemistry; Gene; Long terminal repeat; RNA; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001758406,0.0002349247,0.000159716,0.0001474921,0.0002665917,0.0003210271,0.0001448415,0.0001854794,0.0009180431],"category_scores_gemma":[0.0002402802,0.0002090594,0.0002173862,0.0001104415,0.0002389259,0.0002191631,0.000226999,0.0003290918,0.0004476253],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003173439,"about_ca_system_score_gemma":0.0001637995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004945294,"about_ca_topic_score_gemma":0.0006429275,"domain_scores_codex":[0.9998368,0.00004251587,0.0000086028,0.00003255493,0.00004196256,0.00003760169],"domain_scores_gemma":[0.9999057,0.00001809731,0.00002579653,0.000007847326,0.0000157028,0.00002691145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009603953,0.0000121423,0.0004712392,0.00001098787,0.000002882826,0.00008681432,0.00001713195,0.00002970219,0.9985049,0.00007594463,0.00002962067,0.0006625648],"study_design_scores_gemma":[0.00003932828,0.000254974,0.0359993,0.000009108984,0.00001664509,0.0008820003,0.0000923276,0.004336703,0.9557582,0.000261604,0.002341471,0.000008430509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963851,0.00131595,0.001412014,0.00007722969,0.0000142755,0.00000721692,0.00004275413,0.00002491302,0.0007205618],"genre_scores_gemma":[0.9971026,0.0005571402,0.001112498,0.0000330991,0.000007098177,0.000009413974,0.00009828727,0.00001207989,0.001067731],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009180431,"threshold_uncertainty_score":0.003071129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01555684978346594,"score_gpt":0.2797690045480271,"score_spread":0.2642121547645612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}