{"id":"W2150495344","doi":"10.1093/brain/awq168","title":"SH3TC2, a protein mutant in Charcot–Marie–Tooth neuropathy, links peripheral nerve myelination to endosomal recycling","year":2010,"lang":"en","type":"article","venue":"Brain","topic":"Hereditary Neurological Disorders","field":"Neuroscience","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Deutsche Forschungsgemeinschaft; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University College Cork; RWTH Aachen University; Vanderbilt University Medical Center; Vanderbilt University; National Science Foundation","keywords":"Schwann cell; Endosome; Myelin; Cell biology; Peripheral nervous system; Biology; Peripheral neuropathy; Peripheral myelin protein 22; Neuroscience; Intracellular; Central nervous system; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004927887,0.0002676148,0.0002466234,0.0001992919,0.0001414159,0.0001076963,0.0005465655,0.0002701185,0.0003009061],"category_scores_gemma":[0.01090244,0.0002529499,0.0000875428,0.0006816968,0.0001238284,0.0002951555,0.0002059419,0.001462306,0.0001777171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003210969,"about_ca_system_score_gemma":0.00007670125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008809858,"about_ca_topic_score_gemma":0.0004065188,"domain_scores_codex":[0.9970824,0.0004853417,0.0004494058,0.0009027853,0.0004299174,0.0006501355],"domain_scores_gemma":[0.9987071,0.000508427,0.00009385884,0.0004206039,0.00003113062,0.0002388562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001077795,0.0001734992,0.000766043,0.00001065209,6.154207e-7,0.0004433114,0.000370993,0.000161773,0.9811867,0.00150606,0.0000717964,0.01520073],"study_design_scores_gemma":[0.005848437,0.003448921,0.181826,0.0001420875,0.00001278983,0.0002601443,0.0001921896,0.05906201,0.6651587,0.01072472,0.07101944,0.002304466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980199,0.000005762534,0.0001464776,0.01596586,0.0006423904,0.001167538,0.00002222368,0.0002104039,0.001640365],"genre_scores_gemma":[0.9902177,0.000002227917,0.0004529356,0.008437364,0.000281585,0.0001781095,0.000004595938,0.00004927222,0.0003761855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.316028,"threshold_uncertainty_score":0.9999923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02247644965375123,"score_gpt":0.2634433029872639,"score_spread":0.2409668533335127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}