{"id":"W2150499711","doi":"10.1242/jcs.141788","title":"A role for the CB-associated SUMO isopeptidase USPL1 in RNAPII-mediated snRNA transcription","year":2014,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Wellcome Trust; University of Dundee; University of Ottawa; Alexander von Humboldt-Stiftung","keywords":"snRNP; Cajal body; Biology; Small nuclear RNA; Cell biology; Spliceosome; Prp24; RNA splicing; RNA polymerase II; Gene knockdown; Transcription (linguistics); Small nuclear ribonucleoprotein; Genetics; RNA; Gene expression; Gene; Non-coding RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001678764,0.0002216667,0.0002344235,0.0002411238,0.0002649142,0.0004320288,0.0001880203,0.0003089545,0.0007157472],"category_scores_gemma":[0.0001372839,0.0001288802,0.0002281436,0.00009858818,0.000284039,0.000294721,0.0002518866,0.0003414929,0.0003429439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004545451,"about_ca_system_score_gemma":0.0002058492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005055932,"about_ca_topic_score_gemma":0.0005322998,"domain_scores_codex":[0.9999251,0.000009508815,0.000007136766,0.00002370992,0.00001834913,0.00001617839],"domain_scores_gemma":[0.9998955,0.00001430101,0.00002543083,0.00001517127,0.00001271153,0.00003691757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001062633,0.00001319151,0.0007163375,0.00003728266,0.000003316186,0.000127049,0.00001531024,0.00005733504,0.9966165,0.0003120772,0.00004181704,0.001953573],"study_design_scores_gemma":[0.00001422642,0.00007924697,0.01125634,0.000007688042,0.00001275354,0.0005032444,0.0000294103,0.001635402,0.9837234,0.000224415,0.002507814,0.000006115406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896914,0.004295505,0.00415743,0.0002116329,0.00002054498,0.00001225235,0.0002364344,0.0001095716,0.001265223],"genre_scores_gemma":[0.9963344,0.0006069754,0.001783701,0.00002969905,0.000006314905,0.000007291947,0.000196557,0.00000979995,0.001025223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007157472,"threshold_uncertainty_score":0.003297985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009094832104773631,"score_gpt":0.2578005962237828,"score_spread":0.2487057641190092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}