{"id":"W2150499711","doi":"10.1242/jcs.141788","title":"A role for the CB-associated SUMO isopeptidase USPL1 in RNAPII-mediated snRNA transcription","year":2014,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Wellcome Trust; University of Dundee; University of Ottawa; Alexander von Humboldt-Stiftung","keywords":"snRNP; Cajal body; Biology; Small nuclear RNA; Cell biology; Spliceosome; Prp24; RNA splicing; RNA polymerase II; Gene knockdown; Transcription (linguistics); Small nuclear ribonucleoprotein; Genetics; RNA; Gene expression; Gene; Non-coding RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002308614,0.00006449364,0.00009900378,0.00008530917,0.0001295092,0.00005721307,0.0004314026,0.00004790042,0.000007325984],"category_scores_gemma":[0.0006481163,0.00004146472,0.00008064084,0.0002500858,0.0001413965,0.00001736364,0.00002637767,0.0001313343,0.000002020837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003327708,"about_ca_system_score_gemma":0.0001871131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003278515,"about_ca_topic_score_gemma":0.0001462398,"domain_scores_codex":[0.999007,0.00005721197,0.0002278612,0.0001239105,0.0003020923,0.0002819316],"domain_scores_gemma":[0.9993345,0.0000674707,0.0001487331,0.0001216055,0.0002177247,0.0001099373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007430807,0.00005850142,0.0009518879,0.000003676542,0.000004126663,8.734127e-7,0.00005592584,0.0001547732,0.9970958,0.0000120023,0.0002795308,0.001308562],"study_design_scores_gemma":[0.002543453,0.001202006,0.0193041,0.00004486152,0.00001362295,0.00001555986,0.0003127406,0.01998761,0.9440325,0.0001673625,0.01222775,0.0001483979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968555,0.0002771401,0.001842101,0.0004238247,0.00008520416,0.0001114572,0.000002968542,0.000001292045,0.0004004963],"genre_scores_gemma":[0.9988997,0.0001509116,0.0002095288,0.0001637701,0.00009862786,0.000003272835,0.000002290791,0.000005310138,0.000466586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0530633,"threshold_uncertainty_score":0.1690882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009094832104773631,"score_gpt":0.2578005962237828,"score_spread":0.2487057641190092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}